ArticleMedical & biological engineering & computing2021
Numerical investigation of patient-specific thoracic aortic aneurysms and comparison with normal subject via computational fluid dynamics (CFD).
Article in Medical & biological engineering & computing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Systematic Review of the Application of Computational Fluid Dynamics for Adult Aortic Diseases.Reviews in cardiovascular medicine · 2023Pooled it
- Efficacy evaluation and parametric study of the novel concave triple branched stent graft system based on hemodynamic analysis of first-in-man cases.Quantitative imaging in medicine and surgery · 2026Article
- Estimating flow division in aortic branches of diseased aorta: a method for boundary condition specification in CFD analysis.Frontiers in bioengineering and biotechnology · 2025Article
- ML-ROM wall shear stress prediction in patient-specific vascular pathologies under a limited clinical training data regime.PloS one · 2025Article
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Analysis of Umbilical Artery Hemodynamics in Development of Intrauterine Growth Restriction Using Computational Fluid Dynamics with Doppler Ultrasound.Bioengineering (Basel, Switzerland) · 2024Article
- Computational Modeling Approach to Profile Hemodynamical Behavior in a Healthy Aorta.Bioengineering (Basel, Switzerland) · 2024Article
- Stress Load and Ascending Aortic Aneurysms: An Observational, Longitudinal, Single-Center Study Using Computational Fluid Dynamics.Bioengineering (Basel, Switzerland) · 2024Article
- Analysis of Postoperative Remodeling Characteristics after Modular Inner Branched Stent-Graft Treatment of Aortic Arch Pathologies Using Computational Fluid Dynamics.Bioengineering (Basel, Switzerland) · 2023Article
- Non-invasive diagnostics of blockage growth in the descending aorta-computational approach.Medical & biological engineering & computing · 2022Article
- Effect of left ventricular assist device on the hemodynamics of a patient-specific left heart.Medical & biological engineering & computing · 2022Article
- Investigation of the correlation between cardiac parameters and aortic diameter in patients with ascending aortic aneurysm.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022Article
- Vascular effects of continuous hyperbaric oxygen exposure: experimental outlook.Medical gas researchArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular hemodynamics play an important role in cardiovascular diseases. This work aimed to investigate the effects of an increase in ascending aortic diameter (AAD) on hemodynamics throughout a cardiac cycle for real patients. In this study, two scans of thoracic aortic aneurysm (TAA) subject with different AADs (42.94 mm and 48.01 mm) and a scan of a normal subject (19.81 mm) were analyzed to assess the effects of hemodynamics on the progression of TAA with the same flow rate. Real-patient aortic geometries were scanned by computed tomography angiography (CTA), and steady and pulsatile flow conditions were used to simulate real patient aortic geometries. Aortic arches were obtained from routine clinical scans. Computational fluid dynamics (CFD) simulations were performed with in vivo boundary conditions, and 3D Navier-Stokes equations were solved by a UDF (user-defined function) code defining a real cardiac cycle of one patient using Fourier series (FS). Wall shear stress (WSS) and pressure distributions were presented from normal subject to TAA cases. The results show that during the peak systolic phase pressure load increased by 18.56% from normal subject to TAA case 1 and by 23.8% from normal subject to TAA case 2 in the aneurysm region. It is concluded that although overall WSS increased in aneurysm cases but was low in dilatation areas. As a result, abnormal changes in WSS and higher pressure load may lead to rupture and risk of further dilatation. CFD simulations were highly effective to guide clinical predictions and assess the progress of aneurysm regions in case of early surgical intervention. Graphical abstract.
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