Evidence map›Paper›PMID 33225415›Full record

ArticleDiabetologia2021

Lifetime risk of diabetes in metropolitan cities in India.

Shammi Luhar, Dimple Kondal, Rebecca Jones, Ranjit M Anjana, Shivani A Patel, Sanjay Kinra, Lynda Clarke, Mohammed K Ali, Dorairaj Prabhakaran, M Masood Kadir and 3 more

Abstract read
In one paragraph

Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Observational
  7. Archives of Razi Institute · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Genetic variation inJournal of diabetes and metabolic disorders · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shammi LuharDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK. sl989@medschl.cam.ac.uk.ORCID 0000-0002-1080-8893
Dimple KondalCentre for Chronic Disease Control (CCDC), New Delhi, India.ORCID 0000-0002-1417-9510
Rebecca JonesNutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.
Ranjit M AnjanaMadras Diabetes Research Foundation, Chennai, India.ORCID 0000-0002-4843-1374
Shivani A PatelHubert Department of Global Health, Emory University, Atlanta, GA, USA.ORCID 0000-0003-0082-5857
Sanjay KinraDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-6690-4625
Lynda ClarkeDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Mohammed K AliHubert Department of Global Health, Emory University, Atlanta, GA, USA.ORCID 0000-0001-7266-2503
Dorairaj PrabhakaranCentre for Chronic Disease Control (CCDC), New Delhi, India.ORCID 0000-0002-3172-834X
M Masood KadirDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID 0000-0002-1029-4490
Nikhil TandonDepartment of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0003-4604-1986
Viswanathan MohanMadras Diabetes Research Foundation, Chennai, India.ORCID 0000-0001-5038-6210
K M Venkat NarayanHubert Department of Global Health, Emory University, Atlanta, GA, USA.ORCID 0000-0001-8621-5405

Funding

Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in IndiaR01HL125442 · NHLBI · EMORY UNIVERSITY · PI PRABHAKARAN, DORAIRAJ, WEBER, MARY BETH · 2015 to 2019
$3.3M
Integrated Tracking, Referral, and Algorithmic Management (I-TREC) System for Hypertension and DiabetesU01HL138635 · NHLBI · ALL-INDIA INSTITUTE OF MEDICAL SCIENCES · PI TANDON, NIKHIL · 2017 to 2021
$1.3M
Health systems & implementation sciences institute for NCDs in SoAsia & LatinAmD43TW009135 · FIC · EMORY UNIVERSITY · PI LOZANO, RAFAEL, NARAYAN, KABAYAM M VENKAT · 2012 to 2016
$1.1M
FIC NIH HHS D43 TW009135NHLBI NIH HHS HHSN268200900026CNHLBI NIH HHS R01 HL125442NHLBI NIH HHS U01 HL138635NIDDK NIH HHS P30 DK111024
6 · The paper itself

Abstract

aims/hypothesisWe aimed to estimate the lifetime risk of diabetes and diabetes-free life expectancy in metropolitan cities in India among the population aged 20 years or more, and their variation by sex, age and BMI.

methodsA Markov simulation model was adopted to estimate age-, sex- and BMI-specific lifetime risk of developing diabetes and diabetes-free life expectancy. The main data inputs used were as follows: age-, sex- and BMI-specific incidence rates of diabetes in urban India taken from the Centre for Cardiometabolic Risk Reduction in South Asia (2010-2018); age-, sex- and urban-specific rates of mortality from period lifetables reported by the Government of India (2014); and prevalence of diabetes from the Indian Council for Medical Research INdia DIABetes study (2008-2015).

resultsLifetime risk (95% CI) of diabetes in 20-year-old men and women was 55.5 (51.6, 59.7)% and 64.6 (60.0, 69.5)%, respectively. Women generally had a higher lifetime risk across the lifespan. Remaining lifetime risk (95% CI) declined with age to 37.7 (30.1, 46.7)% at age 60 years among women and 27.5 (23.1, 32.4)% in men. Lifetime risk (95% CI) was highest among obese Indians: 86.0 (76.6, 91.5)% among 20-year-old women and 86.9 (75.4, 93.8)% among men. We identified considerably higher diabetes-free life expectancy at lower levels of BMI. CONCLUSIONS/

interpretationLifetime risk of diabetes in metropolitan cities in India is alarming across the spectrum of weight and rises dramatically with higher BMI. Prevention of diabetes among metropolitan Indians of all ages is an urgent national priority, particularly given the rapid increase in urban obesogenic environments across the country. Graphical abstract.

Indexed as

Urban HealthAdultAge DistributionDiabetes MellitusDisease-Free SurvivalFemaleHumansIncidenceIndiaLife ExpectancyMaleMarkov ChainsMiddle AgedModels, TheoreticalObesityPrevalenceBody mass indexDiabetesDiabetes-free life expectancyIndiaLifetime riskMetropolitan citiesUrban

Identifiers

PMID33225415
PMCPMC7864818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.