Evidence map›Paper›PMID 33225254›Full record

ArticleWater research X2020

Inactivation of RNA and DNA viruses in water by copper and silver ions and their synergistic effect.

Mona Y M Soliman, Gertjan Medema, Boris Estrada Bonilla, Stan J J Brouns, Doris van Halem

Abstract read
In one paragraph

Article in Water research X, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Targeting multidrug-resistantMaterials today. Bio · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Synergistic Antiviral Effects of Metal Oxides and Carbon Nanotubes.International journal of molecular sciences · 2022
    Article
  11. Review
  12. Article
  13. Advances in Understanding of the Copper Homeostasis inInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mona Y M SolimanDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628, CN Delft, the Netherlands.
Gertjan MedemaDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628, CN Delft, the Netherlands.
Boris Estrada BonillaDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, 2629, HZ Delft, the Netherlands.
Stan J J BrounsDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, 2629, HZ Delft, the Netherlands.
Doris van HalemDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628, CN Delft, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cu and Ag have been used as bactericidal agents since ancient times, yet their antiviral capacity in water remains poorly understood. This study tested the effect of copper (Cu) and silver (Ag) on model RNA and DNA viruses MS2 and PhiX 174 in solution at pH 6-8. Cu caused MS2 inactivation with similar rates at pH 6 and 7 but was inert towards PhiX 174 regardless of pH. Ag inactivated both viruses, causing denaturation of MS2 and loss of capsid spikes in PhiX 174. Ag inactivation rates were pH dependent and increased with increasing pH. At pH 8, 6.5 logs of PhiX were inactivated after 3 h and 3 logs of MS2 after only 10 min. The combined use of Cu and Ag revealed synergy in disinfecting MS2 at pH ≥ 7. Although metal concentrations used were higher than the desired values for drinking water treatment, the results prove a promising potential of Cu and Ag combinations as efficient viricidal agents.

Indexed as

MetalsMS2 bacteriophagePhiX 174SynergyVirusWater

Identifiers

PMID33225254
PMCPMC7663217

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.