ReviewBrain hemorrhages2021
COVID-19 and stroke: A review.
Review in Brain hemorrhages, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Association between SARS-CoV-2 and stroke: perspectives from a metaumbrella-review.BMC neurology · 2025Pooled it
- Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: incidence, risk factors, and pathogenesis - a systematic review and meta-analysis.F1000Research · 2021Pooled it
- Preceding Infections and Coagulation Biomarkers in Early-Onset Cryptogenic Ischemic Stroke.Stroke · 2026Observational
- Syphilis Co-Infection Among People Living with HIV in Romania: Epidemiological and Clinical Characteristics in a Single-Center Retrospective Study.Pathogens (Basel, Switzerland) · 2026Article
- MicroRNA-451 Regulates Angiogenesis in Intracerebral Hemorrhage by Targeting Macrophage Migration Inhibitory Factor.Molecular neurobiology · 2024Article
- New Directions in Infection-Associated Ischemic Stroke.Journal of clinical neurology (Seoul, Korea) · 2024Review
- Increased time to surgery and worse perioperative outcome in benign brain tumor patients with COVID-19.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2023Article
- Enhanced Gait Recovery in Chronic Post-COVID-19 Stroke: The Role of Combined Physical Rehabilitation.Reports (MDPI) · 2023Article
- Clinicopathologic Analysis of COVID-19 Associated Thrombi in the Setting of Large Vessel Occlusion: A Prospective Case-Control Study.Stroke (Hoboken, N.J.) · 2023Article
- Stroke Risk Related to Coronavirus Disease-2019: What Have We Learned?Critical care nursing clinics of North America · 2023Review
- Antiphospholipid antibodies in patients with stroke during COVID-19: A role in the signaling pathway leading to platelet activation.Frontiers in immunology · 2023Article
- Coronavirus disease-19 is associated with decreased treatment access and worsened outcomes in malignant brain tumor patients.Surgical neurology international · 2023Article
- Age and sex-specific stroke epidemiology in COVID-19.Frontiers in stroke · 2023Article
- Roles of Interleukin-6-mediated immunometabolic reprogramming in COVID-19 and other viral infection-associated diseases.International immunopharmacology · 2022Review
- Review
- SARS-CoV-2 involvement in central nervous system tissue damage.Neural regeneration research · 2022Review
- Ischemic Stroke and SARS-CoV-2 Infection: The Bidirectional Pathology and Risk Morbidities.Neurology international · 2022Review
- Neuropsychological Outcomes in Adult Patients and Survivors of COVID-19.Pathogens (Basel, Switzerland) · 2022Review
- COVID-19-Associated Acute Asymmetric Hemorrhagic Necrotizing Encephalopathy: A Case Report.The Neurohospitalist · 2022Article
- Case report of a fulminant non-aneurysmal convexity subarachnoid hemorrhage after COVID-19.Interdisciplinary neurosurgery : Advanced techniques and case management · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
COVID-19 patients have presented with a wide range of neurological disorders, among which stroke is the most devastating. We have reviewed current studies, case series, and case reports with a focus on COVID-19 patients complicated with stroke, and presented the current understanding of stroke in this patient population. As evidenced by increased D-dimer, fibrinogen, factor VIII and von Willebrand factor, SARS-CoV-2 infection induces coagulopathy, disrupts endothelial function, and promotes hypercoagulative state. Collectively, it predisposes patients to cerebrovascular events. Additionally, due to the unprecedented strain on the healthcare system, stroke care has been inevitably compromised. The underlying mechanism between COVID-19 and stroke warrants further study, so does the development of an effective therapeutic or preventive intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.