Evidence map›Paper›PMID 33225090›Full record

ArticleHeliyon2020

Bioactive role of plant stress hormone methyl jasmonate against lipopolysaccharide induced arthritis.

S M Gunjegaonkar, S B Wankhede, T S Shanmugarajan, S D Shinde

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. 7-Hydroxyflavone Mitigates OsteoporosisCurrent topics in medicinal chemistry · 2025
    Article
  2. Article
  3. Therapeutic Potential of Plant Oxylipins.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S M GunjegaonkarJSPM's Charak College of Pharmacy and Research, Department of Pharmacology, Gate No. 720/1&2, Pune-Nagar Road, Wagholi, 412207, Pune, Maharashtra, India.
S B WankhedeJSPM's Charak College of Pharmacy and Research, Department of Pharmaceutical Chemistry, Gate No. 720/1&2, Pune-Nagar Road, Wagholi, 412207, Pune, Maharashtra, India.
T S ShanmugarajanVels Institute of Science, Technology and Advanced Studies, School of Pharmaceutical Sciences, Department of Pharmaceutics, Velan Nagar, P. V. Vaithiyalingam Road, Pallavaram, Chennai, 600 117, Tamil Nadu, India.
S D ShindeShri. R. D. Bhakt College of Pharmacy, Department of Pharmacology, Jalna 431203, Maharashtra, India.
Hindu College of Pharmacy · INVels University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current investigation was carried out to screen antiarthritic potential of Methyl Jasmonate (MJ) against lipopolysaccharide (LPS) induced arthritis. Cartilage damage was induced in experimental animals by intraplantar administration of LPS (1 mg/kg) and antiarthritic effect of MJ was screened in two doses of MJ-1 (20 mg/kg), MJ-2 (40 mg/kg) by intraperitoneally administration. Indomethacin (30 mg/kg p.o.) was used as standard drug. The severity of arthritis was evaluated by assessing arthritis score, secondary lesions, motility test, stair climbing ability, and dorsal flexion pain score method. The estimation of blood cytokine tumor necrosis factor- aplha (TNF-α),interleukine (IL-2 and IL-6) and thymus/spleen index was carried out to access the severity of inflammation. Estimation of hepaticenzymatic antioxidant activity superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx)and radiological examination was carried out on 28

Indexed as

AntiarthriticAnti-inflammatoryAntioxidantBiological sciencesLipopolysaccharideMethyl jasmonateMolecular biologyPharmaceutical scienceProteinsToxicology

Identifiers

PMID33225090
PMCPMC7666351
OpenAlexW3105890682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.