Evidence map›Paper›PMID 33225041›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020

Prevalence and clinical correlates of dementia among COVID-19-related deaths in Italy.

Marco Canevelli, Luigi Palmieri, Valeria Raparelli, Cinzia Lo Noce, Elisa Colaizzo, Dorina Tiple, Luana Vaianella, Nicola Vanacore, Silvio Brusaferro, Graziano Onder and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Meta-Analysis of Atrial Fibrillation in Patients With COVID-19.The American journal of cardiology · 2021
    Pooled it
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  12. Observational
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  15. The Impact of the COVID-19 Pandemic on the Cognition of People with Dementia.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco CanevelliNational Center for Disease Prevention and Health Promotion Istituto Superiore di Sanità Rome Italy.
Luigi PalmieriDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging Istituto Superiore di Sanità Rome Italy.
Valeria RaparelliDepartment of Experimental Medicine Sapienza University of Rome Rome Italy.
Cinzia Lo NoceDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging Istituto Superiore di Sanità Rome Italy.
Elisa ColaizzoDepartment of Neuroscience Istituto Superiore di Sanità Rome Italy.
Dorina TipleDepartment of Neuroscience Istituto Superiore di Sanità Rome Italy.
Luana VaianellaDepartment of Neuroscience Istituto Superiore di Sanità Rome Italy.
Nicola VanacoreDepartment of Human Neuroscience Sapienza University of Rome Rome Italy.
Silvio BrusaferroOffice of the President Istituto Superiore di Sanità Rome Italy.
Graziano OnderDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging Istituto Superiore di Sanità Rome Italy.
Italian National Institute of Health COVID‐19 Mortality Group*

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed at exploring the proportion of patients dying with COVID-19 and concomitant dementia in Italy, as well as their clinical characteristics and trajectories of care.

methodsThe proportion of COVID-19-related deaths occurring in people with dementia and the clinical characteristics of deceased individuals according to their dementia status were explored by considering the medical charts of a representative sample of patients deceased in Italian hospitals (n = 2621).

resultsA total of 415 individuals with dementia were identified in the study population, accounting for 15.8% of overall COVID-19-related deaths. Patients with dementia less frequently presented with cough, had lower chance of receiving supportive therapies and intensive care approaches, and showed a faster clinical worsening as compared with individuals with intact cognition. DISCUSSION: Dementia confers a relevant risk of adverse outcomes in case of SARS-CoV-2 infection and influences the clinical presentation, course and management of affected individuals.

Indexed as

COVID‐19dementiapublic healthSARS‐CoV‐2

Identifiers

PMID33225041
PMCPMC7666428

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.