ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020
Longitudinal assessment of dementia measures in Down syndrome.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- Specialists' perceptions of clinical instruments, practices, and staging of DS-AD: Results from an international survey.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Eye Tracking as a Tool for Detecting Alzheimer's Disease in People With Down Syndrome.Journal of intellectual disability research : JIDR · 2025Article
- Longitudinal investigation of gait and Alzheimer's disease in adults with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Assessment of cognitive function in individuals with Down syndrome and dementia: a systematic review.Dementia & neuropsychologia · 2025Review
- Does Employment Complexity Promote Healthy Cognitive Aging in Down Syndrome?Journal of intellectual disabilities : JOID · 2024Article
- Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Insomnia Symptoms Are Associated with Measures of Functional Deterioration and Dementia Status in Adults with Down Syndrome at High Risk for Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Article
- Increased plasma DYRK1A with aging may protect against neurodegenerative diseases.Translational psychiatry · 2023Article
- Timing of Alzheimer's Disease by Intellectual Disability Level in Down Syndrome.Journal of Alzheimer's disease : JAD · 2023Article
- Serious Games for Executive Functions Training for Adults with Intellectual Disability: Overview.International journal of environmental research and public health · 2022Review
- Cognitive outcome measures for tracking Alzheimer's disease in Down syndrome.International review of research in developmental disabilities · 2022Article
- Identifying dementia in Down syndrome with the Severe Impairment Battery, Brief Praxis Test and Dementia Scale for People with Learning Disabilities.Journal of intellectual disability research : JIDR · 2021Article
- Executive Functioning in Adults with Down Syndrome: Machine-Learning-Based Prediction of Inhibitory Capacity.International journal of environmental research and public health · 2021Article
- Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models.Brain sciences · 2021Article
- Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome.Brain sciences · 2021Article
- Longitudinal assessment of dementia measures in Down syndrome.Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
- Physical activity as a resistance or resilience mechanism in Down syndrome Alzheimer's disease.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
introductionEarly detection of dementia symptoms is critical in Down syndrome (DS) but complicated by clinical assessment barriers. The current study aimed to characterize cognitive and behavioral impairment using longitudinal trajectories comparing several measures of cognitive and behavioral functioning.
methodsMeasures included global cognitive status (Severe Impairment Battery [SIB]), motor praxis (Brief Praxis Test [BPT]), and clinical dementia informant ratings (Dementia Questionnaire for People with Learning Disabilities [DLD]). One-year reliability was assessed using a two-way mixed effect, consistency, single measurement intraclass correlation among non-demented participants. Longitudinal assessment of SIB, BPT, and DLD was completed using linear mixed effect models.
resultsOne-year reliability (n = 52; 21 male) was moderate for DLD (0.69 to 0.75) and good for SIB (0.87) and BPT (0.80). Longitudinal analysis (n = 72) revealed significant age by diagnosis interactions for SIB ( DISCUSSION: Current measures demonstrated moderate to good reliability. Longitudinal analysis revealed that SIB, BPT, and DLD changed with age depending on diagnostic progression; no change rates were dependent on baseline cognition, indicating usefulness across a variety of severity levels in DS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.