Evidence map›Paper›PMID 33224977›Full record

ArticleBioMed research international2020

Prediction of Fluid Responsiveness by Stroke Volume Variation in Children Undergoing Fontan Operation.

Yun'an Song, Huiyan Hou, Jie Bai, Hongbin Gu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. How cardiac output is controlled in a Fontan circulation: an update.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yun'an SongDepartment of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine & National Children's Medical Center (Shanghai), 1678 Dongfang Road, Shanghai 200127, China.ORCID https://orcid.org/0000-0003-3611-2576
Huiyan HouDepartment of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine & National Children's Medical Center (Shanghai), 1678 Dongfang Road, Shanghai 200127, China.ORCID https://orcid.org/0000-0003-1267-9244
Jie BaiDepartment of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine & National Children's Medical Center (Shanghai), 1678 Dongfang Road, Shanghai 200127, China.ORCID https://orcid.org/0000-0001-8424-7702
Hongbin GuDepartment of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine & National Children's Medical Center (Shanghai), 1678 Dongfang Road, Shanghai 200127, China.ORCID https://orcid.org/0000-0002-8993-5608
Shanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFontan operation is a palliative medical procedure performed on children with single-ventricle defects. As postoperative success of the procedure largely depends on the preload volume, it is necessary to maintain an appropriate pressure gradient between the systemic vein and the left atrium to ensure the effective volume of systemic circulation. However, there is a lack of effective indexes to evaluate fluid responsiveness in Fontan patients. Stroke volume variation (SVV) is a dynamic hemodynamic parameter based on cardiopulmonary interaction in mechanical ventilation. This study is aimed at validating the sensitivity and specificity of SVV and central venous pressure (CVP) in assessing the fluid responsiveness of Fontan patients.

methodSixty-four children with single ventricle who underwent modified Fontan operation between May 2018 and January 2020 were included in this study. Patients were administered 10 ml·kg

resultsThe SVV values were 16.28% (25th and 75th percentiles 14.17%-19.24%) and 13.68% (25th and 75th percentiles 12.90%-15.89%) before and after fluid challenge treatment in responders, respectively, and the values were 18.60 ± 1.83 mmHg before and 20.20 ± 2.39 mmHg for CVP after treatment. The AUC of SVV was 0.74 (95% confidence interval (CI) 0.54-0.94,

conclusionSVV exhibited a good predictive value for fluid responsiveness in pediatric Fontan patients. Appropriate fluid therapy according to SVV could improve the cardiac function of such patients.

Indexed as

Stroke VolumeAlbuminsArterial PressureCentral Venous PressureChild, PreschoolFemaleFluid TherapyFontan ProcedureHumansMaleProspective StudiesROC CurveTreatment OutcomeAlbumins

Identifiers

PMID33224977
PMCPMC7669329
OpenAlexW3104496894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.