Evidence map›Paper›PMID 33224970›Full record

ArticleBioMed research international2020

Expression and Functional Characterization of a Novel Antimicrobial Peptide: Human Beta-Defensin 118.

Qian Lin, Kunhong Xie, Daiwen Chen, Bing Yu, Xiangbing Mao, Jie Yu, Junqiu Luo, Ping Zheng, Yuheng Luo, Hui Yan and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. The future of recombinant host defense peptides.Microbial cell factories · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qian LinInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Kunhong XieInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Daiwen ChenInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Bing YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Xiangbing MaoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jie YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Junqiu LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Ping ZhengInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Yuheng LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Hui YanInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jun HeInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.ORCID https://orcid.org/0000-0002-1963-9766
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsThe DEFB118 protein was obtained by heterologous expression using

resultsThe

conclusionsThese results suggested a novel function of the mammalian defensins, and the antibacterial and anti-inflammatory properties of DEFB118 may allow it as a potential substitute for conventionally used antibiotics or drugs.

Indexed as

AnimalsAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalApoptosisBacterial AdhesionCell LineDefensinsErythrocytesEscherichia coliEscherichia coli InfectionsGene ExpressionHemolysisHumansIntestinal MucosaMicrobial Sensitivity TestsRecombinant ProteinsAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalDEFB118 protein, humanDefensinsRecombinant Proteins

Identifiers

PMID33224970
PMCPMC7673234
OpenAlexW3100032343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.