Evidence map›Paper›PMID 33224941›Full record

ArticleFrontiers in physics2020

Radioactive Beams in Particle Therapy: Past, Present, and Future.

Marco Durante, Katia Parodi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Emerging technologies for cancer therapy using accelerated particles.Progress in particle and nuclear physics · 2023
    Article
  8. Review
  9. Particle radiotherapy for breast cancer.Frontiers in oncology · 2023
    Review
  10. Article
  11. Depth dose measurements in water forNuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment · 2022
    Article
  12. Higgs Boson: Chapel Hill, CERN, QUB.The Ulster medical journal · 2022
    Article
  13. The history of ion beam therapy in Germany.Zeitschrift fur medizinische Physik · 2022
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marco DuranteBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany.
Katia ParodiDepartment of Experimental Physics-Medical Physics, Ludwig-Maximilians-Universität München, Munich, Germany.
Ludwig-Maximilians-Universität München · DETechnical University of Darmstadt · DE

Funding

European Research Council 883425
6 · The paper itself

Abstract

Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize the beam. Positron-emitting ions that can be visualized with PET imaging were already studied for therapy application during the pilot therapy project at the Lawrence Berkeley Laboratory, and later within the EULIMA EU project, the GSI therapy trial in Germany, MEDICIS at CERN, and at HIMAC in Japan. The results show that radioactive ion beams provide a large improvement in image quality and signal-to-noise ratio compared to stable ions. The main hindrance toward a clinical use of radioactive ions is their challenging production and the low intensities of the beams. New research projects are ongoing in Europe and Japan to assess the advantages of radioactive ion beams for therapy, to develop new detectors, and to build sources of radioactive ions for medical synchrotrons.

Indexed as

carbon ionsoxygen ionsparticle therapyPETradioactive ion beams

Identifiers

PMID33224941
PMCPMC7116396
OpenAlexW3081686800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.