Evidence map›Paper›PMID 33224883›Full record

ArticleFrontiers in oncology2020

Five microRNAs in Serum Are Able to Differentiate Breast Cancer Patients From Healthy Individuals.

Andrea Feliciano, Lucila González, Yoelsis Garcia-Mayea, Cristina Mir, Mireia Artola, Nieves Barragán, Remedios Martín, Anna Altés, Josep Castellvi, Sergi Benavente and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Review
  5. Serums miR-24-3p and miR-1301-3p as Potential Biomarkers in MEN1 Syndrome.International journal of molecular sciences · 2025
    Article
  6. Observational
  7. Article
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  9. Review
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Andrea FelicianoBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Lucila GonzálezBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Yoelsis Garcia-MayeaBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Cristina MirBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Mireia ArtolaPrimary Care Center CAP-Vallcarca-Sant Gervasi, Barcelona, Spain.
Nieves BarragánPrimary Care Center CAP-Vallcarca-Sant Gervasi, Barcelona, Spain.
Remedios MartínPrimary Care Center CAP-Vallcarca-Sant Gervasi, Barcelona, Spain.
Anna AltésPrimary Care Center CAP-Vallcarca-Sant Gervasi, Barcelona, Spain.
Josep CastellviBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Sergi BenaventeBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Santiago Ramón Y CajalBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Martín Espinosa-BravoBreast Pathology Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Javier CortésInstitute of Breast Cancer, Quiron Group, Barcelona, Spain.
Isabel T RubioBreast Surgical Oncology, University of Navarra Clinic, Madrid, Spain.
Matilde E LLeonartBiomedical Research in Cancer Stem Cells Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Vall d'Hebron Institut de Recerca · ESConsorci d’Atenció Primària de Salut Barcelona Esquerra · ESClinica Universidad de Navarra · ESUniversitat Autònoma de Barcelona · ESVall d'Hebron Hospital Universitari · ESVall d'Hebron Institute of Oncology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the cancer with the most incidence and mortality in women. microRNAs are emerging as novel prognosis/diagnostic tools. Our aim was to identify a serum microRNA signature useful to predict cancer development. We focused on studying the expression levels of 30 microRNAs in the serum of 96 breast cancer patients

Indexed as

breast cancerdiagnosismicroRNAsprognosisserum

Identifiers

PMID33224883
PMCPMC7670964
OpenAlexW3096584898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.