ArticleGland surgery2020
Bilateral pneumothorax in a patient with anaplastic thyroid carcinoma and lung metastasis during lenvatinib therapy: a case report.
Article in Gland surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Tumor microenvironment-guided targeted and immunotherapy in anaplastic thyroid cancer: a literature review from preclinical models to clinical translation.Translational cancer research · 2026Review
- Anaplastic thyroid cancer: Genetic roles, targeted therapy, and immunotherapy.Genes & diseases · 2025Review
- Recurrent Drug-Induced Pneumothorax Associated With Lenvatinib: A Case Report.Respirology case reports · 2025Article
- Lenvatinib treatment strategy for thyroid carcinoma with malignant pleurisy: a case report.Gland surgery · 2024Article
- Article
- Lung cavitation in patients with anaplastic thyroid cancer treated with lenvatinib.Gland surgery · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prognosis of anaplastic thyroid carcinoma (ATC) is very poor. In most patients, ATC presents with cervical lymph node metastasis, and more than 40% of patients have distant metastasis at the time of diagnosis. Lenvatinib, a multi-targeted tyrosine kinase inhibitor, is a novel drug that has antitumor effects on radioactive iodine-refractory papillary cancer and anaplastic cancer. The development of bilateral pneumothorax during targeted therapy is very rare in patients with thyroid cancer. We recently encountered a case of bilateral pneumothorax in a patient with ATC and lung metastasis during lenvatinib therapy. The patient underwent video-assisted thoracoscopic surgery (VATS) in both the lungs because the pneumothorax continued to aggravate even after the insertion of chest tubes. Clinicians need to be aware that the development of pneumothorax is a possibility during lenvatinib therapy for ATC and lung metastasis. The case is reported herein, along with a review of relevant literature.
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