Evidence map›Paper›PMID 33224819›Full record

ArticleGland surgery2020

The correlation between blood lipids and clinicopathological features of breast cancer in young females.

Wei Jin, Benjie Shan, Hu Liu, Wenjuan Li, Qianyu Zhang, Shoubing Zhou, Dandan Hu, Yueyin Pan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gland surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wei JinThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Benjie ShanDepartment of Tumor Chemotherapy, the First Affiliated Hospital of the USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Hu LiuThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Wenjuan LiThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Qianyu ZhangThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Shoubing ZhouThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Dandan HuThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
Yueyin PanThe Fifth Ward of the Department of Tumor Chemotherapy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China & Anhui Provincial Cancer Hospital, Hefei, China.
University of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is becoming more common in young adults. The relationships between blood lipids and breast cancer have been widely studied in recent years. In our current study, we investigated the potential correlations between blood lipids and clinicopathological features of breast cancer in young females.

methodsFifty-nine young adults (40 years or younger) with pathologically confirmed invasive breast cancer that were treated in our center from October 2015 to March 2020 were enrolled in this study. These patients were divided into the negative group (n=40, with normal blood lipids) and positive group (n=19, with abnormal blood lipids) according to the preoperative blood lipid profiles, and differences in the clinicopathological features were compared between these two groups.

resultsCompared with the negative group, the positive group had a significantly higher rate of lymph node positivity (P=0.034); compared with the positive group, the negative group had a significantly higher rate of HER2 positivity (P=0.029). However, these two groups showed no significant difference in tumor size, molecular type, clinical stage, histological grade, tumor thrombus, and Ki-67 index (P values were 0.071, 0.227, 0.593, 0.396, 0.198, and 0.593, respectively).

conclusionsBlood lipid level has a certain correlation with lymph node metastasis and HER2 expression in young breast cancer patients. Therefore, blood lipid levels has a certain reference value in the clinical treatment of breast cancer.

Indexed as

blood lipidsBreast cancerclinicopathological featuresyoung females

Identifiers

PMID33224819
PMCPMC7667059
OpenAlexW3093216489

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.