Evidence map›Paper›PMID 33224816›Full record

ArticleGland surgery2020

Propofol-based total intravenous anesthesia decreases the incidence of postoperative nausea and vomiting without affecting flap survival in free flap breast reconstruction.

Li Yang, Ya-Jun Xu, Jian Shen, Fei-Fei Lou, Jun Zhang, Jiong Wu

Open access · diamondAbstract read
In one paragraph

Article in Gland surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li YangDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Ya-Jun XuDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Jian ShenDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Fei-Fei LouDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Jun ZhangDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Jiong WuDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative nausea and vomiting (PONV) may cause undesirable effects after microsurgical breast reconstruction. Although total intravenous anesthesia (TIVA) with propofol has been demonstrated to be effective in reducing PONV, it has not been assessed in autologous free flap breast reconstruction. The purpose of this study was to investigate the antiemetic prophylaxis effect and safety of TIVA in microvascular breast reconstruction.

methodsEighty-three patients undergoing microsurgical breast reconstruction with propofol (31 patients) or sevoflurane (52 patients) were retrospectively reviewed. The incidence of PONV was assessed at 2, 6, and 24 hours after surgery. Mean arterial blood pressure (MAP) was compared at T

resultsThe incidence of nausea was significantly reduced in the TIVA group over 0 to 2 hours period (P

conclusionsCompared with sevoflurane maintaining anesthesia, propofol-based TIVA improves PONV with less fluctuation of MAP, and did not affect flap survival.

Indexed as

deep inferior epigastric perforator flap (DIEP flap)postoperative nausea and vomiting (PONV)sevofluraneTotal intravenous anesthesia (TIVA)

Identifiers

PMID33224816
PMCPMC7667098
OpenAlexW3083962829

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.