ArticleCurrent behavioral neuroscience reports2019
Biological responses to acute stress and suicide: A review and opportunities for methodological innovation.
Article in Current behavioral neuroscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights.medRxiv : the preprint server for health sciences · 2025Article
- Intersection of adverse childhood experiences, suicide and overdose prevention.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2024Review
- A History of Suicide Attempt Is Associated with Increased Sympathetic Activation in Bipolar Disorder.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2024Article
- Investigation of peripheral inflammatory biomarkers in association with suicide risk in major depressive disorder.Frontiers in psychiatry · 2024Article
- When Stress Accumulates: Interacting Effects of Childhood Adversity, Multidimensional Victimization, and Protective Resources on Adolescent Suicidal Behaviors.Chronic stress (Thousand Oaks, Calif.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
purpose of reviewWhile rates of other medical illnesses have declined over the past several decades, rates of suicide have increased, particularly among adolescents. Prior research on biological underpinnings of suicide risk has remained limited. In this review, we describe a recent model conceptualizing suicide as a failure of biological responses to acute stress. According to this model, youth who fail to mount an adaptive stress response following exposure to a stressor are at acute risk for suicide. RECENT
findingsAlthough much more research is needed, early evidence suggests that abnormal biological responses to acute stress, such as altered autonomic nervous system activity and altered hypothalamic-pituitary-adrenal axis function, may underlie risk for suicide, particularly during the transition to adolescence. SUMMARY: Overall, initial evidence supports a link between biological responses to acute stress and suicide risk. However, future work that incorporates makers of other biological and environmental systems will sharpen our understanding of who is at suicide risk and when this risk is highest.
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Registered trials
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