Evidence map›Paper›PMID 33224644›Full record

ArticleCureus2020

Warfarin Dosing Requirement According to Body Mass Index.

Abdullah Alshammari, Abdullah Altuwayjiri, Ziad Alshaharani, Rami Bustami, Hind S Almodaimegh

Abstract read
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdullah AlshammariPharmaceutical Care Department, King Abdullah Medical City, Makkah, SAU.
Abdullah AltuwayjiriPharmaceutical Department, King Fahad Medical City, Riyadh, SAU.
Ziad AlshaharaniCollege of Pharmacy, King Saud Bin Abdulaziz University for Health Science, Riyadh, SAU.
Rami BustamiCollege of Pharmacy, Alfaisal University, Riyadh, SAU.
Hind S AlmodaimeghPharmaceutical Care Department, Ministry of National Guard Health Affaire - King Abdulaziz Medical City, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Many factors affect the required dose of warfarin, including body weight, which is mentioned only in a few studies. Our study was conducted using body mass index (BMI) to assess the requirements for warfarin dosing. Methods A retrospective study was conducted that included adults who used warfarin for more than three months, with at least two consecutive international ratio (INR) readings within the therapeutic range. Results Over 301 patients were included; the 20% higher dose of warfarin was required in obese patients than normal BMI and overweight patients (32.2 ± 15.2 vs. 27.4 ±17.3 and 26.8 ± 12.7; p=0.013, respectively). Conclusion Obese patients required a higher dose than other patients, which should be considered when initiating or adjusting the warfarin dose.

Indexed as

anticoagulant therapyobesityvitamin k antagonistwarfarinweight

Identifiers

PMID33224644
PMCPMC7676436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.