Evidence map›Paper›PMID 33224624›Full record

ArticleACS macro letters2020

Synthesis of Carboxy-Dimethylmaleic Amide Linked Polymer Conjugate Based Ultra-pH-sensitive Nanoparticles for Enhanced Antitumor Immunotherapy.

Shuyao Lang, Zibin Tan, Xuanjun Wu, Xuefei Huang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS macro letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuyao LangDepartment of Chemistry and Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan 48824, United States.
Zibin TanDepartment of Chemistry and Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan 48824, United States.
Xuanjun WuDepartment of Chemistry and Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan 48824, United States.ORCID 0000-0002-7399-6916
Xuefei HuangDepartment of Chemistry, Institute for Quantitative Health Science and Engineering, and Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan 48824, United States.ORCID 0000-0002-6468-5526
Michigan State University · US

Funding

Generation of active immunity against cytotoxic oligomeric tau speciesR01CA225105 · NCI · MICHIGAN STATE UNIVERSITY · PI HUANG, XUEFEI · 2018 to 2023
$2.8M
NCI NIH HHS R01 CA225105
6 · The paper itself

Abstract

Cytotoxic T lymphocytes (CTLs) are an important tool for anticancer immunotherapy. To elicit powerful CTL activities, ultra-pH-sensitive nanoparticles (NPs) based on methoxy poly(ethylene glycol)-

Identifiers

PMID33224624
PMCPMC7676757
OpenAlexW3097934614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.