Evidence map›Paper›PMID 33224595›Full record

ArticleAmerican journal of cardiovascular disease2020

Leptin concentrations in type 2 diabetes and non-diabetes Nigerian-Africans.

Obiageli Uzoamaka Onyemelukwe, Dimie Ogoina, Geoffrey Chukwubuike Onyemelukwe

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Obiageli Uzoamaka OnyemelukweDepartment of Medicine, Ahmadu Bello University (ABU) Teaching Hospital Zaria, Nigeria.
Dimie OgoinaDepartment of Medicine, Niger Delta University Teaching Hospital Okolobiri, Bayelsa, Nigeria.
Geoffrey Chukwubuike OnyemelukweDepartment of Medicine, Ahmadu Bello University (ABU) Teaching Hospital Zaria, Nigeria.
Ahmadu Bello University Teaching Hospital · NGNiger Delta University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most studies on leptin in diabetes mellitus (DM) compared to healthy controls were done in Caucasians, with conflicting findings. Paucity of data on this exists in Nigerian-Africans. Therefore, the study determined plasma leptin concentrations in newly diagnosed type-2 diabetes versus controls and its relation to obesity/demographic-metabolic indices. A cross-sectional comparative study on 154 subjects: 67 diabetes and 87 healthy controls at the Ahmadu Bello University Teaching Hospital, Nigeria. Leptin was determined by the sandwich enzyme-linked immunosorbent assay. Mann-Whitney U test, Spearman's Correlation and Step-wise Multiple Logistic Regression analysis of Log-transformed variables determined outcomes. Leptin trended towards lower levels in DM subjects than controls when both sexes were combined, though insignificant (

Indexed as

healthy controlsinsulin resistanceLeptinNigerian-Africansobesity indicestype 2 diabetes mellitus

Identifiers

PMID33224595
PMCPMC7675163
OpenAlexW3108178942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.