Evidence map›Paper›PMID 33224581›Full record

ArticleAmerican journal of cardiovascular disease2020

Deep sedation vs femoral block anesthesia: beat-by-beat hemodynamic impact on TAVI procedure.

Salvatore Mario Romano, Francesca Ristalli, Cristina Giglioli, Francesco Meucci, Miroslava Stolcova, Giorgio Jacopo Baldereschi, Emanuele Cecchi, Giovanni Squillantini, Francesco Ciappi, Niccolò Marchionni and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Local anesthesia alone versus with sedation for transcatheter aortic valve implantation: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Salvatore Mario RomanoExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Francesca RistalliStructural Interventional Cardiology, Cardio-Thoraco-Vascular Department, Careggi University Hospital Florence, Italy.
Cristina GiglioliExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Francesco MeucciStructural Interventional Cardiology, Cardio-Thoraco-Vascular Department, Careggi University Hospital Florence, Italy.
Miroslava StolcovaStructural Interventional Cardiology, Cardio-Thoraco-Vascular Department, Careggi University Hospital Florence, Italy.
Giorgio Jacopo BaldereschiExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Emanuele CecchiExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Giovanni SquillantiniStructural Interventional Cardiology, Cardio-Thoraco-Vascular Department, Careggi University Hospital Florence, Italy.
Francesco CiappiExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Niccolò MarchionniExperimental and Clinical Medicine Department, University Hospital Florence Italy.
Carlo Di MarioStructural Interventional Cardiology, Cardio-Thoraco-Vascular Department, Careggi University Hospital Florence, Italy.
Didier PayenUniversity Paris 7 Denis Diderot, Paris, Sorbonne, Cité Paris, France.
University of Florence · ITAzienda Ospedaliero-Universitaria Careggi · ITDélégation Paris 7 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn spite of the increased use of Trans-catheter Aortic Valve Implantation (TAVI) due to the better patient selection, well-trained operators and improved technology, the choice of the best anesthesia regimen remains an open question. In particular, it remains to be clarified whether deep sedation (DS) in spontaneous breathing or femoral local anesthesia (LA) is best.

objectiveThis study compared the hemodynamic variations determined by deep sedation (DS) with spontaneous breathing and local femoral anesthesia (LA) in 2 groups of patients submitted to TAVI with two different kinds of anesthesia, using a beat-by-beat pulse contour method (MostCare

methods82 patients with severe aortic stenosis and similar baseline characteristics and indications underwent trans-femoral TAVI: 50 with LA and 32 with DS. All patients were submitted to minimally invasive hemodynamic monitoring. The following parameters were measured:

resultsThe TAVI procedure was successful in 89% of patients (VARC-2 criteria) with no difference between the 2 groups. Anesthesia induction determined a higher decrease of pressures in DS than in LA (P<0.01) with no differences in CO. The VAC parameters (Ea

conclusionThe use of the pulse contour method to track the fast-hemodynamic changes during the TAVI procedure proved suitable for the aim. As expected, LA and DS induced different pre-TAVI hemodynamic conditions, which influenced the post-TAVI hemodynamic changes. The hemodynamic conditions induced by LA, enabled the occurrence of post-TAVI aortic regurgitation to be detected more effectively.

Indexed as

Anesthesia and TAVI procedurecontinuous hemodynamic monitoringdeep sedation or femoral block anesthesiaevaluation of residual regurgitationpulse contour analysis

Identifiers

PMID33224581
PMCPMC7675158
OpenAlexW3108168927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.