Evidence map›Paper›PMID 33224574›Full record

ReviewAmerican journal of cardiovascular disease2020

Echocardiographic evaluation of right ventricular-arterial coupling in pulmonary hypertension.

Maria Chiara Todaro, Scipione Carerj, Concetta Zito, Maria Paola Trifirò, Giovanni Consolo, Bijoy Khandheria

Open access · greenAbstract readReview
In one paragraph

Review in American journal of cardiovascular disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Bridging the Gap: Exploring Right Ventricular-Pulmonary Artery Coupling in Acute Coronary syndrome-A Pilot Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
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  12. LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Maria Chiara TodaroDepartment of Cardiology, Papardo Hospital Messina, Italy.
Scipione CarerjDepartment of Clinical and Experimental Medicine - Cardiology Unit - University of Messina Messina, Italy.
Concetta ZitoDepartment of Clinical and Experimental Medicine - Cardiology Unit - University of Messina Messina, Italy.
Maria Paola TrifiròDepartment of Cardiology, Papardo Hospital Messina, Italy.
Giovanni ConsoloDepartment of Cardiology, Papardo Hospital Messina, Italy.
Bijoy KhandheriaAurora Research Institute, Aurora Health Care Milwaukee, WI, Italy.
Azienda Ospedaliera Ospedali Riuniti Papardo Piemonte · ITUniversity of Messina · ITAurora Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a hemodynamic condition characterized by chronically elevated mean pulmonary artery pressure (m-PAP ≥ 25 mmHg) measured at rest by right heart catheterization (RHC). It includes a pre-capillary and a post-capillary form. Pulmonary artery hypertension (PAH) is a pre-capillary form of PH potentially generated by several heterogeneous systemic disorders, whose main hemodynamic change is represented by severely increased pulmonary vascular resistance (PVR). In order to preserve an efficient right ventricular-arterial (RV-PA) coupling, the right ventricle (RV) adapts to this chronic increase of its afterload, with a compensatory hypertrophy, until RV dilatation and dysfunction occur. Right ventricular (RV) function and especially RV-PA coupling assessment showed to be very important prognostic markers in this subset of patients, especially for those with pre-capillary PH. The aim of this review is to provide a pathophysiological insight into the spectrum of RV adaptive changes occurring in response to chronic increase of RV afterload and to present the role of echocardiographic parameters as possible tools for early non-invasive evaluation of RV-PA coupling, before overt heart failure ensues.

Indexed as

echocardiographyPulmonary hypertensionright ventricular-arterial coupling

Identifiers

PMID33224574
PMCPMC7675169
OpenAlexW3109002915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.