Evidence map›Paper›PMID 33224566›Full record

ReviewAmerican journal of blood research2020

Treatment protocols for BK virus associated hemorrhagic cystitis after hematopoietic stem cell transplantation.

Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod, Seyed Asadollah Mousavi

Open access · greenAbstract readReview
In one paragraph

Review in American journal of blood research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maryam Mohammadi NajafabadiDepartment of Hematology, Faculty of Medical Science, Tarbiat Modares University Tehran, Iran.
Masoud SoleimaniDepartment of Hematology, Faculty of Medical Science, Tarbiat Modares University Tehran, Iran.
Mohammad AhmadvandHematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences Tehran, Iran.
Mina Soufi ZomorrodApplied Cell Sciences Department, Faculty of Medical Sciences, Tarbiat Modares University Tehran, Iran.
Seyed Asadollah MousaviHematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences Tehran, Iran.
Tarbiat Modares University · IRStem Cell Technology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HSCT) represents a vital curative choice for many disease. However its outcome can be hampered by a variety of transplant associated complications. Hemorrhagic cystitis (HC) considered as one of the major difficulties after HSCT. HC symptoms comprise hematuria, dysuria, burning during urination, urinary frequency, urgency and incontinency, abdominal or suprapubic pain, urinary obstruction, and renal or bladder damage. There are a lot of causes for HC development. BK virus reactivation is one of the major causes of HC after HSCT. There is still no standard and approved treatment protocol for BK virus associated HC (BKV-HC). Treatment of HC is according to the local standard operating procedures, depending on the cause and severity. In this study we will review the current treatments available for this disease. We have divided the therapeutic procedures into 5 categories including conservative therapy, complimentary options, surgical procedures, pharmacological treatments and adoptive cell therapy. We believe that comparing the advantages and disadvantages of different therapies make it easier to choose the best treatment protocol. In addition, we had a greater focus on adoptive cell therapy, because it is a relatively new introduced method and might be a logical alternative to conventional treatments for refractory patients. In total, no definitive recommendation is possible for current available treatments because these procedures have only been utilized sporadically in a limit number of patients. Furthermore, a number of treatment options are only experimental and definitely need more effort.

Indexed as

BK viruscidofovirhematopoietic stem cell transplantationhemorrhagic cystitis

Identifiers

PMID33224566
PMCPMC7675133
OpenAlexW3110329089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.