ArticleJournal of ophthalmology2020
Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia.
Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- School-related sedentary behaviours and indicators of health and well-being among children and youth: a systematic review.The international journal of behavioral nutrition and physical activity · 2022Pooled it
- Prevalence and incidence of myopia and high myopia among children and adolescents in Qingdao, China (2022-2024): a longitudinal study.BMC public health · 2026Article
- Article
- Cross-sectional study of myopia prevalence and associated risk factors among children and adolescents in Shaanxi Province, China, in 2021.Annals of medicine · 2025Article
- Research Progress of Epigenetic Modifications in Myopia.International journal of medical sciences · 2025Review
- Establishing and Validating Refractive Error Reference Values for Myopia Prediction Among Children Aged 6-12 Years - Jiangsu Province, China, 2018-2023.China CDC weekly · 2024Article
- Review
- Review
- Associations betweenBiomedicines · 2024Article
- The Impact of Sunshine Duration on Myopia in Central China: Insights from Populational and Spatial Analysis in Hubei.International journal of general medicine · 2024Article
- Sleep and its association with dental caries or myopia in first graders.Nursing open · 2024Article
- Regional disparities in the prevalence and correlated factors of myopia in children and adolescents in Gansu, China.Frontiers in medicine · 2024Article
- Effects of Insufficient Sleep on Myopia in Children: A Systematic Review and Meta-Analysis.Nature and science of sleep · 2024Review
- Article
- Machine learning to analyze the factors influencing myopia in students of different school periods.Frontiers in public health · 2023Article
- Time spent outdoors as an intervention for myopia prevention and control in children: an overview of systematic reviews.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022Review
- Trend of myopia through different interventions from 2010 to 2050: Findings from Eastern Chinese student surveillance study.Frontiers in medicine · 2022Article
- Association of Axial Length and Refraction with Near Horizontal Heterophoria in Chinese Children: An Observational Cross-Sectional Study.Journal of ophthalmology · 2022Article
- Association of sleep quality with myopia based on different genetic risk levels.International journal of ophthalmology · 2022Article
- Relationship between Family and Myopia: Based on the Jiangsu School Student Myopia Study.Journal of ophthalmology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to evaluate the effect of genetic-environmental interaction on myopia in Chinese children aged 6 to 9 years.
methodsStudents had the physical examination and were required to provide basic demographic information. Their families were asked to fill in a questionnaire concerning factors related to myopia. Multiple regression analysis was performed, and adjusted risk ratio values were calculated to assess the role between gene and environment. Value of the environmental and genetic index (EGI) was calculated to demonstrate the effect of genetic-environmental interaction on myopia.
resultsThe prevalence of myopia maintained at a high level. EGI was calculated as 0.125 suggesting that genetic factors may play the 12.5% role in the formation of myopia and environmental factors may play a role of 87.5% in the formation of myopia.
conclusionsFor young pupils aged 6 to 9 years, myopia prevalence maintained at a high level, and duration of homework time and staring at electronic screen were the strongest factors associated with myopia. The calculated value of EGI was low, which suggests that environmental factors may play the leading role in the formation of myopia. A long-term follow-up research to improve the accuracy value of EGI is our next job.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.