Evidence map›Paper›PMID 33224144›Full record

ArticleFrontiers in immunology2020

Case Report: A Case of X-Linked Agammaglobulinemia With High Serum IgE Levels and Allergic Rhinitis.

Bianca Cinicola, Andrea Uva, Lucia Leonardi, Daniele Moratto, Silvia Giliani, Rita Carsetti, Simona Ferrari, Anna Maria Zicari, Marzia Duse

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Bianca CinicolaDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Andrea UvaDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Lucia LeonardiDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Daniele MorattoCytogenetic and Medical Genetics Unit, "A. Nocivelli" Institute for Molecular Medicine Spedali Civili Hospital, Brescia, Italy.
Silvia GilianiCytogenetic and Medical Genetics Unit, "A. Nocivelli" Institute for Molecular Medicine Spedali Civili Hospital, Brescia, Italy.
Rita CarsettiB Cell Physiopathology Unit, Immunology Research Area, Bambino Gesù Children Hospital, Rome, Italy.
Simona FerrariMedical Genetics Unit, S.Orsola-Malpighi University Hospital, Bologna, Italy.
Anna Maria ZicariDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Marzia DuseDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITBambino Gesù Children's Hospital · ITPoliclinico S.Orsola-Malpighi · ITPoliclinico Umberto I · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked Agammaglobulinemia (XLA) is a rare genetic disorder of B-lymphocyte differentiation, characterized by the absence or paucity of circulating B cells, markedly reduced levels of all serum immunoglobulin isotypes and lack of specific antibody production. Bruton Tyrosine Kinase (

Indexed as

Agammaglobulinaemia Tyrosine KinaseAgammaglobulinemiaB-LymphocytesCell DifferentiationChildGenetic Diseases, X-LinkedHumansImmunoglobulin EMaleMutationPhenotypeRhinitis, AllergicUp-RegulationAgammaglobulinaemia Tyrosine KinaseBTK protein, humanImmunoglobulin EallergyBTK geneIgE productionmild phenotypeprotein expressionX-linked Agammaglobulinemia

Identifiers

PMID33224144
PMCPMC7674281
OpenAlexW3095455120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.