Evidence map›Paper›PMID 33223974›Full record

Trial reportJournal of interventional cardiology2020

Impact of Lesion Preparation Technique on Side Branch Compromise in Calcified Coronary Bifurcations: A Subgroup Analysis of the PREPARE-CALC Trial.

Abdelhakim Allali, Mohamed Abdel-Wahab, Hussein Traboulsi, Rayyan Hemetsberger, Nader Mankerious, Robert Byrne, Volker Geist, Mohamed El-Mawardy, Dmitriy Sulimov, Ralph Toelg and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Intravascular Lithotripsy for Calcific Coronary Bifurcations: Procedural Success and 1-Year Clinical Outcomes.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Observational
  5. Article
  6. Review
  7. Percutaneous coronary intervention for calcified and resistant lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Review
  8. Article
  9. SCAI Expert Consensus Statement on the Management of Calcified Coronary Lesions.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  10. Rotational atherectomy of calcified coronary lesions: current practice and insights from two randomized trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
    Review
  11. The 17th expert consensus document of the European Bifurcation Club - techniques to preserve access to the side branch during stepwise provisional stenting.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  12. Review
  13. Review
  14. Percutaneous coronary intervention of bifurcation lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
  15. Angiographic predictors of unplanned rotational atherectomy in complex calcified coronary artery disease: a pooled analysis from the randomised ROTAXUS and PREPARE-CALC trials.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
  16. Feasibility and safety of minimal-contrast IVUS-guided rotational atherectomy for complex calcified coronary artery disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  17. Review
  18. Intravascular Lithotripsy for Calcified Left Main Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdelhakim AllaliCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.ORCID https://orcid.org/0000-0002-5285-6789
Mohamed Abdel-WahabCardiology Department, Heart Center Leipzig at the University of Leipzig, Leipzig, Germany.
Hussein TraboulsiCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.
Rayyan HemetsbergerCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.
Nader MankeriousCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.
Robert ByrneCardiology Department, German Heart Center, Technical University of Munich, Munich, Germany.
Volker GeistCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.
Mohamed El-MawardyCardiology Department, Vivantes Wenckebach Hospital, Berlin, Germany.
Dmitriy SulimovCardiology Department, Heart Center Leipzig at the University of Leipzig, Leipzig, Germany.
Ralph ToelgCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.
Gert RichardtCardiology Department, Heart Center Segeberger Kliniken, Bad Segeberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyze the impact of different techniques of lesion preparation of severely calcified coronary bifurcation lesions.

backgroundThe impact of different techniques of lesion preparation of severely calcified coronary bifurcation lesions is poorly investigated.

methodsWe performed an as-treated analysis on 47 calcified bifurcation lesions treated with scoring/cutting balloons (SCB) and 68 lesions treated with rotational atherectomy (RA) in the PREPARE-CALC trial. Compromised side branch (SB) as assessed in the final angiogram was the primary outcome measure and was defined as any significant stenosis, dissection, or thrombolysis in myocardial infarction flow <3.

resultsTrue bifurcation lesions were present in 49% vs. 43% of cases in the SCB and RA groups, respectively. After stent implantation, SB balloon dilatation was necessary in around one-third of cases (36% vs. 38%;

conclusionsIn the PREPARE-CALC trial, side branch compromise was more frequently observed after lesion preparation with SCB as compared with RA. Consequently, in calcified bifurcation lesions, an upfront debulking with an RA-based strategy might optimize the result in the side branch.

Indexed as

Angioplasty, Balloon, CoronaryAtherectomy, CoronaryCoronary Artery DiseaseCoronary VesselsPostoperative ComplicationsVascular CalcificationAgedCoronary AngiographyFemaleHumansMaleOutcome and Process Assessment, Health CareRisk Adjustment

Identifiers

PMID33223974
PMCPMC7673940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.