Evidence map›Paper›PMID 33223957›Full record

ArticleMediators of inflammation2020

Baicalin Liposome Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Inhibiting TLR4/JNK/ERK/NF-

Yu Long, Yan Xiang, Songyu Liu, Yulu Zhang, Jinyan Wan, Qiyue Yang, Mingquan Cui, Zhimin Ci, Nan Li, Wei Peng

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  4. Article
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  6. Nanotechnology-Based Therapeutics for Airway Inflammatory Diseases.Clinical reviews in allergy & immunology · 2025
    Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yu Long *School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yan Xiang *School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Songyu LiuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yulu ZhangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jinyan WanSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Qiyue YangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Mingquan CuiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Zhimin CiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Nan LiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID https://orcid.org/0000-0002-9255-4638
Wei PengSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID https://orcid.org/0000-0003-0511-9564
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are challenging diseases with the high mortality in a clinical setting. Baicalin (BA) is the main effective constituent isolated from the Chinese medical herb

Indexed as

Gene Expression RegulationAcute Lung InjuryAnimalsArea Under CurveDrug Delivery SystemsDrugs, Chinese HerbalExtracellular Signal-Regulated MAP KinasesFlavonoidsInflammationLipopolysaccharidesLiposomesMaleMAP Kinase Kinase 4Medicine, Chinese TraditionalMiceNF-kappa B p50 SubunitbaicalinDrugs, Chinese HerbalExtracellular Signal-Regulated MAP KinasesFlavonoidsLipopolysaccharidesLiposomesMAP Kinase Kinase 4NF-kappa B p50 SubunitNfkb1 protein, mousePlant ExtractsScutellaria baicalensis extractTlr4 protein, mouseToll-Like Receptor 4

Identifiers

PMID33223957
PMCPMC7673921
OpenAlexW3100909427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.