Evidence map›Paper›PMID 33223955›Full record

ArticleMediators of inflammation2020

Mibefradil and Flunarizine, Two T-Type Calcium Channel Inhibitors, Protect Mice against Lipopolysaccharide-Induced Acute Lung Injury.

Limei Wan, Weibin Wu, Shunjun Jiang, Shanhe Wan, Dongmei Meng, Zhipeng Wang, Jiajie Zhang, Li Wei, Pengjiu Yu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Limei WanThe First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.ORCID https://orcid.org/0000-0003-3925-5943
Weibin WuDepartment of Basic Medicine, Zhaoqing Medical College, Zhaoqing 526020, China.ORCID https://orcid.org/0000-0003-4308-0664
Shunjun JiangDepartment of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-0356-1386
Shanhe WanGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China.ORCID https://orcid.org/0000-0003-3914-8128
Dongmei MengDepartment of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-8756-7987
Zhipeng WangDepartment of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-7284-4996
Jiajie ZhangGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China.ORCID https://orcid.org/0000-0002-3510-4040
Li WeiDepartment of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-3246-8770
Pengjiu YuDepartment of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-9968-3280
First Affiliated Hospital of Guangzhou Medical University · CNSouthern Medical University · CNFirst Affiliated Hospital of Guangdong Pharmaceutical University · CNZhaoqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have illuminated that blocking Ca

Indexed as

Acute Lung InjuryAnimalsBronchoalveolar Lavage FluidCalcium Channel BlockersCalcium Channels, T-TypeCytokinesFlunarizineLipopolysaccharidesLungLung InjuryMaleMibefradilMiceMice, Inbred BALB CNF-kappa BSignal TransductionCalcium Channel BlockersCalcium Channels, T-TypeCytokinesFlunarizineLipopolysaccharidesMibefradilNF-kappa B

Identifiers

PMID33223955
PMCPMC7671802
OpenAlexW3105966404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.