ArticleClinical medicine insights. Case reports2020
Role of Emergency Automated Red Cell Exchange in Sickle Cell Crisis: A Case Report.
Article in Clinical medicine insights. Case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- A case report and review of literature on the role of automated red cell exchange in managing sickle cell crisis in India.Asian journal of transfusion scienceArticle
- Therapeutic red blood cell exchange in a sickle cell disease patient with acute bone pain crisis: Our experience in a tertiary care center.Asian journal of transfusion scienceArticle
- Multimodality, multidisciplinary approach to overcome technical challenges in a pediatric stem cell harvest for sickle cell disease with preformed donor-specific antibodies.Asian journal of transfusion scienceArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For many years main stay of treatment for sickle cell anaemia was transfusion therapy. But repeated transfusions put the patient at risk of iron overload. Automated red cell exchange is an evolving and newer technique which rapidly removes the sickle cells and has benefit in decreasing sickle cell load and related complications. Red cell exchange is a therapeutic procedure in which the patient's whole blood is processed centrifugally in cell separator. Patient's red cells are separated from other blood components and removed and replaced with donor red cells and colloids. We report our first experience of automated red cell exchange in 24-year-old female diagnosed case of sickle cell anaemia presented to us with acute chest syndrome with septic shock. Red cell exchange was planned to tide over the acute sickle cell crisis and provide symptomatic improvement. We also highlight that compound heterozygous thalassaemia could be associated with sickle cell disease which could make the diagnosis difficult. New generation automated Apheresis equipment's provides better monitoring of the procedure that can be useful in severely ill patients also.
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