Evidence map›Paper›PMID 33223834›Full record

ArticleSubstance abuse : research and treatment2020

Adolescent Behavioral Characteristics Mediate Familial Effects on Alcohol Use and Problems in College-Bound Students.

April L Brown, Roberto A España, Chelsie E Benca-Bachman, Justine W Welsh, Rohan Hc Palmer

Abstract read
In one paragraph

Article in Substance abuse : research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The MAPme Project: Implementing a College-Based Study of Substance Use and Mental Wellness.International journal of environmental research and public health · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

April L BrownBehavioral Genetics of Addiction Laboratory, Department of Psychology, Emory University, Atlanta, GA, USA.
Roberto A EspañaBehavioral Genetics of Addiction Laboratory, Department of Psychology, Emory University, Atlanta, GA, USA.
Chelsie E Benca-BachmanBehavioral Genetics of Addiction Laboratory, Department of Psychology, Emory University, Atlanta, GA, USA.
Justine W WelshPsychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.
Rohan Hc PalmerBehavioral Genetics of Addiction Laboratory, Department of Psychology, Emory University, Atlanta, GA, USA.ORCID https://orcid.org/0000-0002-6809-9962

Funding

The Kinship Risk Score: An Integrative Tool to Prioritize Alcohol and Drug-Addiction Related Genes for Enhanced Risk PredictionDP1DA042103 · NIDA · EMORY UNIVERSITY · PI PALMER, ROHAN HUGH CRAIG · 2017 to 2021
$2.3M
NIDA NIH HHS DP1 DA042103
6 · The paper itself

Abstract

backgroundStudies suggest a broad spectrum of behaviors associated with drinking. Consequently, it is unclear whether patterns of familial risk for psychopathology are directly or indirectly related to patterns of alcohol use and problems in late adolescence or mediated by behavioral characteristics, such as temperament, mood.

objectivesWe examined direct and indirect effects of perceived family history of psychopathology on pre-collegiate alcohol use and problems via the Transmissible Liability Index (TLI).

methodsParticipants (N = 302; 29.6% male) provided self-report data on age of onset of drinking, past 90-day frequency of alcohol use and problems (AUP), family history of internalizing and alcohol and illicit substance use, and TLI.

resultsApproximately 21% of participants reported having at least one relative with a history of regular and/or problematic alcohol use, compared to 12% for illicit substance use, and -55% for internalizing problems. Higher TLI scores were associated with increased family history of substance use, alcohol use, and internalizing problems, as well as earlier age of onset of drinking. Family history of internalizing problems was the most robust indicator of AUP (β = 0.20 [95% CI = 0.04-0.36],

conclusionsFamily history of internalizing, drinking, and illicit substance use reflect generalized risk for a broad set of behaviors associated with risk for alcohol initiation and use during the transition from high school to college.

Indexed as

adolescent healthalcoholcollegefamily historyTransmissible Liability Index

Identifiers

PMID33223834
PMCPMC7656872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.