Evidence map›Paper›PMID 33223767›Full record

ArticleDiabetes spectrum : a publication of the American Diabetes Association2020

Lipid Profile in Indian Patients With Type 2 Diabetes: The Scope for Atherosclerotic Cardiovascular Disease Risk Reduction.

Chellamma Jayakumari, Puthiyaveettil Khadar Jabbar, Sarayu Soumya, R V Jayakumar, Darvin Vamadevan Das, Gopi Girivishnu, Anjana Gopi, Ramesh Gomez, Ravindranath Sreenath, Abilash Nair

Abstract read
In one paragraph

Article in Diabetes spectrum : a publication of the American Diabetes Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Journal of biomedical research · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Diabetic Uterine Environment Leads to Disorders in Metabolism of Offspring.Frontiers in cell and developmental biology · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chellamma JayakumariDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Puthiyaveettil Khadar JabbarDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Sarayu SoumyaDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
R V JayakumarIndian Institute of Diabetes, Thiruvananthapuram, India.
Darvin Vamadevan DasDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Gopi GirivishnuDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Anjana GopiDepartment of Pediatrics, ESIC Model and Superspecialty Hospital, Kollam, India.
Ramesh GomezDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Ravindranath SreenathDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.
Abilash NairDepartment of Endocrinology and Metabolism, Government Medical College, Thiruvananthapuram, India.ORCID 0000-0001-6776-1582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveReduction of atherosclerotic cardiovascular disease (ASCVD) risk in patients with diabetes requires proper management of lipid parameters. This study aimed to find the pattern of dyslipidemia and scope of ASCVD risk reduction in patients with diabetes by lipid management.

methodsClinical, biochemical, and medication profiles of all patients with diabetes attending a tertiary diabetes care hospital over a 2-year period were collected. The prevalence of various lipid abnormalities was determined after excluding patients with thyroid dysfunction and those on lipid-lowering medications. Patients were stratified according to LDL cholesterol, HDL cholesterol, and triglyceride levels, and other clinical parameters were compared among the groups. The adequacy of statin treatment was assessed based on American Diabetes Association guidelines.

resultsNine hundred and seventy-one patients were included. The prevalence of hyperlipidemia was 40.0%, of whom 14.6% were newly diagnosed. The most common lipid abnormality was elevated LDL cholesterol. Higher A1C and fasting blood glucose values were found to be associated with higher LDL cholesterol levels. Twenty-seven percent of patients with indications for treatment with statins were receiving them. Of those being treated with statins, 42.6% had an LDL cholesterol level ≥100 mg/dL.

conclusionIn South Indian patients with type 2 diabetes and fair glycemic control, high LDL cholesterol is the predominant lipid abnormality. There remains a huge potential for ASCVD risk reduction in this population if the knowledge practice gap is addressed.

Identifiers

PMID33223767
PMCPMC7666608

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