Evidence map›Paper›PMID 33223766›Full record

ArticleJournal of King Saud University. Science2021

Molecular interaction analysis of Sulawesi propolis compounds with SARS-CoV-2 main protease as preliminary study for COVID-19 drug discovery.

Muhamad Sahlan, Rafidha Irdiani, Darin Flamandita, Reza Aditama, Saleh Alfarraj, Mohammad Javed Ansari, Apriliana Cahya Khayrani, Diah Kartika Pratami, Kenny Lischer

Open access · goldAbstract read
In one paragraph

Article in Journal of King Saud University. Science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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  8. Arabian journal of chemistry · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Muhamad SahlanDepartment of Chemical Engineering, Faculty of Engineering University of Indonesia, 16424 Depok, West Java, Indonesia.
Rafidha IrdianiDepartment of Chemical Engineering, Faculty of Engineering University of Indonesia, 16424 Depok, West Java, Indonesia.
Darin FlamanditaDepartment of Chemical Engineering, Faculty of Engineering University of Indonesia, 16424 Depok, West Java, Indonesia.
Reza AditamaDepartment of Chemistry, Bandung Institute of Technology, Jalan Ganeca no 10 Bandung 40132, Indonesia.
Saleh AlfarrajZoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammad Javed AnsariDepartment of Botany, Hindu College Moradabad (MJP Rohilkhand University Bareilly), 244001, India.
Apriliana Cahya KhayraniDepartment of Chemical Engineering, Faculty of Engineering University of Indonesia, 16424 Depok, West Java, Indonesia.
Diah Kartika PratamiLab of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, 12640 Jakarta, Indonesia.
Kenny LischerDepartment of Chemical Engineering, Faculty of Engineering University of Indonesia, 16424 Depok, West Java, Indonesia.
University of Indonesia · IDBandung Institute of Technology · IDKing Saud University · SAM.J.P. Rohilkhand University · INPancasila University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global health concern, as the World Health Organization declared this outbreak to be a global pandemic in March 2020. The need for an effective treatment is urgent because the development of an effective vaccine may take years given the complexity of the virus and its rapid mutation. One promising treatment target for COVID-19 is SARS-CoV-2 main protease. Thus, this study was aimed to examine whether Sulawesi propolis compounds produced by

Indexed as

COVID-19Molecular dockingPotent inhibitorSARS-CoV-2 main proteaseSulawesi propolis

Identifiers

PMID33223766
PMCPMC7670966
OpenAlexW3109717653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.