ArticleBritish journal of experimental pathology1987
Stress induced periosteal changes.
Article in British journal of experimental pathology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Computational mechanobiological model combining epiphyseal, apophyseal, and appositional growth and inner bone remodeling of the juvenile femur.Biomedical engineering online · 2026Article
- Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice.Journal of anatomy · 2026Article
- Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells.Advanced healthcare materials · 2025Article
- Periosteum and development of the tissue-engineered periosteum for guided bone regeneration.Journal of orthopaedic translation · 2022Review
- Bone Geometry Is Altered by Follistatin-Induced Muscle Growth in Young Adult Male Mice.JBMR plus · 2021Article
- Lumbar Scoliosis in Patients With Breast Cancer: Prevalence and Relationship With Breast Cancer Treatment, Age, Bone Mineral Density, and Body Mass Index.Annals of rehabilitation medicine · 2017Article
- High pressures and asymmetrical stresses in the scoliotic disc in the absence of muscle loading.Scoliosis · 2007Article
- Early periosteal changes in translation-induced bone modelling.Journal of anatomy · 1993Article
- Periosteal response in translation-induced bone remodelling.Journal of anatomy · 1990Article
- Periosteal changes in mechanically stressed rat caudal vertebrae.Journal of anatomy · 1989Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tails of Sprague-Dawley rats of approximately 50 g body mass were either left straight or bent to form a loop containing three or five vertebrae (CV). Subsequent treatment was as follows: (a) in situ: segments were removed at 0, 8, 16, 24 h, 3, 5 and 7 days and examined histologically: (b) transplants: skinned segments were transplanted autologously and examined at the same time intervals; (c) normal saline: skinned segments were placed in a 0.9% solution maintained at (i) 4 degrees C and (ii) 37 degrees C and examined 8, 16 and 24 h later. The results show that on bending a bone in situ the remodelling which occurs reflects the displacement of the soft tissues, and more specifically the periosteum, towards or away from the bone surface. Functionally the developing periosteum consists of three zones and when stressed its fibroelastic component moves away from or towards the osteogenic layer either applying tension to it stimulating bone formation, or pressure eventually inducing bone resorption. These changes are mediated via the mid-zone. The effects on the fibroelastic component alone are best seen in transplants or in normal saline at 37 degrees C where the osteogenic layer dies. The periosteum in growing bones is ideally structured to respond rapidly and sensitively to altered strain by initiating adaptive surface remodelling of bone.
Indexed as
Identifiers
3322355PMC2013080W940040846What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.