Evidence map›Paper›PMID 33223023›Full record

ReviewNeurosurgery clinics of North America2021

Extent of Resection of Glioblastoma: A Critical Evaluation in the Molecular Era.

Daniel P Cahill

Open access · greenAbstract readReview
In one paragraph

Review in Neurosurgery clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. SDS-CRISPR for Single-Nucleotide Variant Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Towards Optical Biopsy in Glioma Surgery.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. NKG2C/Journal for immunotherapy of cancer · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daniel P CahillDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Yawkey 9E, Boston, MA 02114, USA. Electronic address: cahill@mgh.harvard.edu.
Harvard University · US

Funding

Targeting the Vasular SystemP50CA165962 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Benjamin Harris Kann · 2013 to 2026
$33.5M
Targeting Nicotinamide Adenine Dinucleotide (NAD+) metabolism in IDH mutant gliomasR01CA227821 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CAHILL, DANIEL P., WAKIMOTO, HIROAKI · 2018 to 2022
$2.4M
NCI NIH HHS P50 CA165962NCI NIH HHS R01 CA227821
6 · The paper itself

Abstract

The work of modern neurosurgical glioma practice combines securing accurate diagnoses, under the 2016 revised World Health Organization (WHO) Classification of Tumors of the Central Nervous System, with an aggressive and safe surgical pursuit of tumor removal. The evidence base that drives clinical decision-making has undergone a critical reevaluation with the incorporation of molecular classifiers into the updated WHO diagnoses including the 3 most common diffuse gliomas in adults: glioblastoma IDH wild-type, astrocytoma IDH mutant, and oligodendroglioma IDH mutant 1p/19q codeleted. The studies that form the foundation of modern practice, and the areas for future inquiry are reviewed.

Indexed as

Neurosurgical ProceduresBrain NeoplasmsGlioblastomaHumansIsocitrate DehydrogenaseNeoplasm, ResidualIDH1 protein, humanIsocitrate DehydrogenaseGliomaIDH1 mutationSurgery

Identifiers

PMID33223023
PMCPMC7742372
OpenAlexW3094724703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.