ArticleJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2020
Intracranial hemorrhage in critically ill patients hospitalized for COVID-19.
Article in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Intracranial hemorrhages in patients with COVID-19: a systematic review of the literature, regarding six cases in an Amazonian population.Arquivos de neuro-psiquiatria · 2023Pooled it
- Neuropathological findings from COVID-19 patients with neurological symptoms argue against a direct brain invasion of SARS-CoV-2: A critical systematic review.European journal of neurology · 2021Pooled it
- A case-based systematic review on the SARS-COVID-2-associated cerebrovascular diseases and the possible virus routes of entry.Journal of neurovirology · 2021Pooled it
- Neuropathologic findings of patients with COVID-19: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Management of COVID-19 associated coagulopathy in critically ill patients and the risk of acquired von willebrand syndrome.Scientific reports · 2025Article
- Article
- The Spectrum of Neuro-COVID is Broader than Frequently Anticipated.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Neuroprotective potentials of ferulic acid against intracerebral hemorrhage COVID-19 through using network pharmacology approach and molecular docking analysis.Current research in toxicology · 2023Article
- Vertebral artery dissecting aneurysm rupture under severe COVID-19.Brain hemorrhages · 2022Article
- SARS-CoV-2 triggered seizure complicated by fatal subdural hematoma under edoxaban and clopidogrel.Journal of family medicine and primary care · 2022Article
- Evaluation of neurological disorders that develop concurrently with COVID-19 pneumonia: a retrospective analysis.Arquivos de neuro-psiquiatria · 2022Article
- Non-Aneurysmal Subarachnoid Hemorrhage in COVID-19: A Case Report and Review of Literature.Medical research archives · 2022Article
- The relationship between COVID-19 infection and intracranial hemorrhage: A systematic review.Brain hemorrhages · 2021Review
- Intracerebral bleeding after Janus-kinase inhibitor baricitinib for COVID-19.Brain hemorrhages · 2021Article
- Clinical patterns of endothelial damage and thrombotic events in two patients with COVID-19: A case report.Clinical case reports · 2021Article
- Intracerebral hemorrhage in COVID-19: A narrative review.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2021Review
- Predictors of intracerebral hemorrhage in COVID-19.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2021Article
- Age-Associated Neurological Complications of COVID-19: A Systematic Review and Meta-Analysis.Frontiers in aging neuroscience · 2021Article
- Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In this study, we report three cases of spontaneous intracranial hemorrhage in patients who were initially hospitalized at our tertiary care center in Washington, DC with symptoms of COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was diagnosed in all three patients, who were critically ill, requiring intubation and ventilatory support. During their protracted hospitalizations, subsequent imaging disclosed intracranial hemorrhages, including intracerebral and subarachnoid hemorrhages, in the context of anticoagulation and coagulopathy. We believe this is related to the tropism of SARS-CoV-2 to the endothelial lining of the cerebral vasculature via their angiotensin-converting enzyme (ACE) II receptors. Given our findings, we advocate heightened vigilance for intracerebral hemorrhage events, and scanning when practicable, in COVID-19 patients which have prolonged ventilatory support and depressed neurologic examinations.
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