Evidence map›Paper›PMID 33222710›Full record

Trial reportPublic health nutrition2021

Predictors of recovery in children aged 6-59 months with uncomplicated severe acute malnutrition: a multicentre study.

Sam Marconi David, Preethi N Ragasudha, Sunita Taneja, Sanjana Brahmawar Mohan, Sharad D Iyengar, Ruby Angeline Pricilla, Jose Martines, Harshpal Singh Sachdev, Virendra Suhalka, Venkata Raghava Mohan and 4 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sam Marconi DavidDepartment of Community Health, Christian Medical College, Vellore, TN, India.
Preethi N RagasudhaDepartment of Community Health, Christian Medical College, Vellore, TN, India.ORCID 0000-0001-6977-3288
Sunita TanejaCentre for Health Research and Development, Society for Applied Studies, New Delhi, India.
Sanjana Brahmawar MohanSitaram Bhartia Institute of Science and Research, New Delhi, India.
Sharad D IyengarAction Research and Training for Health, Udaipur, Rajasthan, India.
Ruby Angeline PricillaDepartment of Community Health, Christian Medical College, Vellore, TN, India.
Jose MartinesCentre for Intervention Science in Maternal and Child Health, Centre for International Health, University of Bergen, Bergen, Norway.
Harshpal Singh SachdevSitaram Bhartia Institute of Science and Research, New Delhi, India.
Virendra SuhalkaAction Research and Training for Health, Udaipur, Rajasthan, India.
Venkata Raghava MohanDepartment of Community Health, Christian Medical College, Vellore, TN, India.
Sarmila MazumderCentre for Health Research and Development, Society for Applied Studies, New Delhi, India.
Ranadip ChowdhuryCentre for Health Research and Development, Society for Applied Studies, New Delhi, India.
Rajiv BahlDepartment of Maternal, Newborn, Child and Adolescent Health, World Health Organisation, Geneva, Switzerland.
Anuradha BoseDepartment of Community Health, Christian Medical College, Vellore, TN, India.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveTo identify predictors of recovery in children with uncomplicated severe acute malnutrition (SAM).

designThis is a secondary data analysis from an individual randomised controlled trial, where children with uncomplicated SAM were randomised to three feeding regimens, namely ready-to-use therapeutic food (RUTF) sourced from Compact India, locally prepared RUTF or augmented home-prepared foods, under two age strata (6-17 months and 18-59 months) for 16 weeks or until recovery. Three sets of predictors that could influence recovery, namely child, family and nutritional predictors, were analysed.

settingRural and urban slum areas of three states of India, namely Rajasthan, Delhi and Tamil Nadu.

participantsIn total, 906 children (age: 6-59 months) were analysed to estimate the adjusted hazard ratio (AHR) using the Cox proportional hazard ratio model to identify various predictors.

resultsBeing a female child (AHR: 1·269 (1·016, 1·584)), better employment status of the child's father (AHR: 1·53 (1·197, 1·95)) and residence in a rental house (AHR: 1·485 (1·137, 1·94)) increased the chances of recovery. No hospitalisation (AHR: 1·778 (1·055, 2·997)), no fever, (AHR: 2·748 (2·161, 3·494)) and ≤ 2 episodes of diarrhoea (AHR: 1·579 (1·035, 2·412)) during the treatment phase; availability of community-based peer support to mothers for feeding (AHR: 1·61 (1·237, 2·097)) and a better weight-for-height Z-score (WHZ) at enrolment (AHR: 1·811 (1·297, 2·529)) predicted higher chances of recovery from SAM.

conclusionThe probability of recovery increases in children with better WHZ and with the initiation of treatment for acute illnesses to avoid hospitalisation, availability of peer support and better employment status of the father.

Indexed as

Severe Acute MalnutritionChildChild, PreschoolFemaleHospitalizationHumansIndiaInfantProportional Hazards ModelsRural PopulationPredictorsReady-to-use therapeutic foodRecoverySevere acute malnutrition

Identifiers

PMID33222710
PMCPMC11094385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.