Evidence map›Paper›PMID 33222612›Full record

ArticleGut microbes2020

Altered gut bacterial and metabolic signatures and their interaction in gestational diabetes mellitus.

Xing Wang, Hongli Liu, Yifan Li, Shuai Huang, Lan Zhang, Chiying Cao, Philip N Baker, Chao Tong, Peng Zheng, Hongbo Qi

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 9 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 9 syntheses or guidelines pooled it, 133 citations in OpenAlex.

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  18. Gut-brain axis in health and brain disease.Chinese medical journal · 2026
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Xing WangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Hongli LiuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Yifan LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Shuai HuangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Lan ZhangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Chiying CaoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Philip N BakerDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Chao TongDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Peng ZhengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Hongbo QiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
First Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence indicates that the gut microbiome can modulate metabolic homeostasis, and thus may influence the development of gestational diabetes mellitus (GDM). However, whether and how the gut microbiome and its correlated metabolites change in GDM is uncertain. Herein we compare the gut microbial compositions, and fecal and urine metabolomes, of 59 patients with GDM versus 48 pregnant healthy controls (HCs). We showed that the microbial and metabolic signatures of GDM patients were significantly different from those of HCs. Compared to HCs, the GDM subjects were characterized by enriched bacterial operational taxonomic units (OTUs) of the family

Indexed as

AdultAmino AcidsBacillotaBlood GlucoseCarbohydrate MetabolismDiabetes, GestationalDysbiosisEnterobacteriaceaeFemaleGastrointestinal MicrobiomeHumansPregnancyRNA, Ribosomal, 16SAmino AcidsBlood GlucoseRNA, Ribosomal, 16SdiagnosisGestational diabetes mellitusgut microbiomemetabolic pathwaysmetabolome

Identifiers

PMID33222612
PMCPMC7714515
OpenAlexW3108737238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.