ArticleGlobal spine journal2022
Average Lumbar Hounsfield Units Predicts Osteoporosis-Related Complications Following Lumbar Spine Fusion.
Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 66 citations in OpenAlex.
- Development and evaluation of a simple CT-based DXA triage score for osteoporosis in candidates for lumbar spine surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Osteoporosis and adult spinal deformity-a review for spinal surgeons by the SRS adult spinal deformity task force on senescence.Spine deformity · 2026Review
- Sarcopenia, paraspinal muscle degeneration, and bone quality as prognostic factors for adjacent segment degeneration or disease after lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Which vertebral levels provide practical HU-based assessment for osteoporosis screening? A comparative analysis from T1 to S2.Journal of orthopaedic surgery and research · 2026Article
- Thai Expert Consensus on Bone Health Optimization for Instrumented Spine Surgery.International journal of spine surgery · 2025Article
- Predictors of Cage Subsidence After Oblique Lumbar Interbody Fusion.Journal of clinical medicine · 2025Article
- Skeletal risk factors for postoperative complications in older men undergoing spinal fusion surgery.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Bone texture by clinical magnetic resonance imaging is directly related to bone tissue maturity by Fourier-transform infrared spectroscopy.JBMR plus · 2025Article
- Development and validation of machine learning models for distal instrumentation-related problems in patients with degenerative lumbar scoliosis based on preoperative CT and MRI.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Factors that influence long term instrumentation stability in patients with unstable thoracolumbar injuries.World journal of orthopedics · 2025Article
- The lowest HU value on transverse planes: a predictive factor for cranial adjacent vertebral fracture risk after percutaneous vertebroplasty.Quantitative imaging in medicine and surgery · 2025Article
- Does Baseline Hounsfield Unit Predict Patients' Outcomes Following Surgical Management of Unstable Osteoporotic Thoracolumbar Fractures?Medicina (Kaunas, Lithuania) · 2025Article
- Hounsfield Unit Utilization in Cervical Spine for Bone Quality Assessment: A Scoping Review.Journal of clinical medicine · 2025Review
- Personalized Approaches to Spine Surgery.International journal of spine surgery · 2024Article
- Do Hounsfield Units From Intraoperative CT Scans Correlate With Preoperative Values?Clinical orthopaedics and related research · 2024Article
- Surgery for spinal deformity with osteoporosis: Achieving successful fusion.Osteoporosis and sarcopenia · 2024Review
- Changes in nail position and antirotation blade angles on the risk of femoral head varus in PFNA fixed patients: a clinical review and comprehensive biomechanical research.European journal of medical research · 2024Article
- The influence of osteoporosis on mechanical complications in lumbar fusion surgery: a systematic review.North American Spine Society journal · 2024Review
- Systematic Review and Meta-Analysis of the Effect of Osteoporosis on Reoperation Rates and Complications after Surgical Management of Lumbar Degenerative Disease.Journal of bone metabolism · 2024Article
- The correlation between self-Hounsfield units and adjacent vertebral fracture after percutaneous vertebral augmentation: a retrospective cohort study.Quantitative imaging in medicine and surgery · 2024Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designRetrospective Study.
objectiveTo compare methods of assessing pre-operative bone density to predict risk for osteoporosis related complications (ORC), defined as proximal junctional kyphosis, pseudarthrosis, accelerated adjacent segment disease, reoperation, compression fracture, and instrument failure following spine fusions.
methodsChart review of primary posterior thoracolumbar or lumbar fusion patients during a 7 year period. Inclusion criteria: preoperative dual-energy x-ray absorptiometry (DXA) test within 1 year and lumbar CT scan within 6 months prior to surgery with minimum of 1 year follow-up. Exclusion criteria: <18 years at time of index procedure, infection, trauma, malignancy, skeletal dysplasia, neuromuscular disorders, or anterior-posterior procedures.
results140 patients were included. The average age was 67.9 years, 83 (59.3%) were female, and 45 (32%) had an ORC. There were no significant differences in patient characteristics between those with and without an ORC. Multilevel fusions were associated with ORCs (46.7% vs 26.3%, p = 0.02). Patients with ORCs had lower DXA t-scores (-1.62 vs -1.10, p = 0.003) and average Hounsfield units (HU) (112.1 vs 148.1, p ≤ 0.001). Multivariable binary logistic regression analysis showed lower average HU (Adj. OR 0.00 595% CI 0.0001-0.1713, p = 0.001) was an independent predictor of an ORC. The odds of an ORC increased by 1.7-fold for every 25 point decrease in average HU.
conclusionsThe gold standard for assessing bone mineral density has been DXA t-scores, but the best predictor of ORC remains unclear. While both lower t-scores and average HU were associated with ORC, only HU was an independent predictor of ORC.
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