Evidence map›Paper›PMID 33222070›Full record

ArticleEnvironmental science and pollution research international2021

Onosma bracteata Wall. induces G

Ajay Kumar, Sandeep Kaur, Kritika Pandit, Varinder Kaur, Sharad Thakur, Satwinderjeet Kaur

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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  6. Exploration of targeted anti-tumor therapy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ajay KumarDepartment of Botanical & Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Sandeep KaurDepartment of Botanical & Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Kritika PanditDepartment of Botanical & Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Varinder KaurIndigenous Education and Research Centre, James Cook University, Australia, Townsville, Douglas Campus, Douglas, QLD, 4811, Australia.
Sharad ThakurDepartment of Molecular Biology & Biochemistry, Guru Nanak Dev University, Amritsar, India.
Satwinderjeet KaurDepartment of Botanical & Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India. satwinderjeet.botenv@gndu.ac.in.
Guru Nanak Dev University · INJames Cook University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Onosma bracteata Wall. (Boraginaceae), commonly known as "gaozaban" is a highly valuable medicinal herb, useful in the treatment of body swellings, abdominal pain, eye-related problems, fever, and urinary calculi. The present study was performed to investigate the antioxidant properties of extract/fractions, viz. ethanol (Obeth) extract, hexane (Obhex) fraction, chloroform (Obcl) fraction, ethyl acetate (Obea) fraction, butanol (Obbu) fraction, and aqueous (Obaq) fraction isolated from O. bracteata. Obea fraction showed stronger free radical quenching ability in various antioxidant assays, as compared to the other fractions. Obea fraction with effective free radical-scavenging properties was further evaluated for the antiproliferative activity against human osteosarcoma MG-63, human neuroblastoma IMR-32, and human lung cancer A549 cell lines using MTT assay. Obea fraction showed strong cytotoxicity with GI

Indexed as

BoraginaceaeOsteosarcomaApoptosisCell Line, TumorCyclin EGlycogen Synthase Kinase 3 betaHumansPlant ExtractsProto-Oncogene Proteins c-aktReactive Oxygen SpeciesCyclin EGlycogen Synthase Kinase 3 betaPlant ExtractsProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAntioxidantAntiproliferativeApoptosisCell cycle arrestOnosma bracteataOsteosarcomaROS

Identifiers

PMID33222070
OpenAlexW3108097988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.