Evidence map›Paper›PMID 33221954›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2021

The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells.

Christelle Fayad, Hassib Audi, Rony S Khnayzer, Costantine F Daher

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Novel phenanthroline-based ruthenium complex as a promising antimicrobial agent.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  4. Review
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  6. Review
  7. Article
  8. The Antioxidant and Proapoptotic Effects ofPlants (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Potent Chlorambucil-Platinum(IV) Prodrugs.International journal of molecular sciences · 2022
    Article
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christelle FayadNatural Sciences Department, Lebanese American University, Byblos, Lebanon.
Hassib AudiDepartment of Natural Sciences, Lebanese American University, Chouran, Beirut, Lebanon.
Rony S KhnayzerDepartment of Natural Sciences, Lebanese American University, Chouran, Beirut, Lebanon. rony.khnayzer@lau.edu.lb.ORCID 0000-0001-7775-0027
Costantine F DaherNatural Sciences Department, Lebanese American University, Byblos, Lebanon. cdaher@lau.edu.lb.ORCID 0000-0002-8275-7263
Lebanese American University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruthenium complexes have been recently reported as potential chemotherapeutic agents that offer tumor selectivity and low tumor resistance. This study investigates the photochemistry and the effect of four strained photoactivatable polypyridyl ruthenium(II) complexes on non-small-cell lung cancer (A549) and triple negative breast cancer (MDA-MB-231) cells. All four ruthenium(II) complexes, [Ru(bpy)

Indexed as

AnimalsAntineoplastic AgentsApoptosisCarcinoma, Non-Small-Cell LungCell Line, TumorCoordination ComplexesHumansLightLung NeoplasmsMesenchymal Stem CellsPhotosensitizing AgentsPyridinesRatsReactive Oxygen SpeciesRutheniumTriple Negative Breast NeoplasmsAntineoplastic AgentsCoordination ComplexesPhotosensitizing AgentsPyridinesReactive Oxygen SpeciesRutheniumA549ApoptosisCytotoxicityMDA-MB-231Photoactivated chemotherapyPolypyridyl ruthenium(II)

Identifiers

PMID33221954
OpenAlexW3108829242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.