Evidence map›Paper›PMID 33221817›Full record

ReviewCell death & disease2020

Current biomarker-associated procedures of cancer modeling-a reference in the context of IDH1 mutant glioma.

Narges Zare Mehrjardi, Daniel Hänggi, Ulf Dietrich Kahlert

Open access · goldAbstract readReview
In one paragraph

Review in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. DKK3 Expression in Glioblastoma: Correlations with Biomolecular Markers.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Narges Zare MehrjardiClinic for Neurosurgery, Medical Faculty Heinrich-Heine University, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Daniel HänggiClinic for Neurosurgery, Medical Faculty Heinrich-Heine University, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Ulf Dietrich KahlertClinic for Neurosurgery, Medical Faculty Heinrich-Heine University, Moorenstrasse 5, 40225, Duesseldorf, Germany. mail@ulf-kahlert.com.
Heinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isocitrate dehydrogenases (IDH1/2) are central molecular markers for glioblastoma. Providing in vitro or in vivo models with mutated IDH1/2 can help prepare facilities to understand the biology of these mutated genes as glioma markers, as well as help, improve therapeutic strategies. In this review, we first summarize the biology principles of IDH and its mutations and outline the core primary findings in the clinical context of neuro-oncology. Given the extensive research interest and exciting developments in current stem cell biology and genome editing, the central part of the manuscript is dedicated to introducing various routes of disease modeling strategies of IDH mutation (IDH

Indexed as

BiomarkersGliomaHumansIsocitrate DehydrogenaseBiomarkersIDH1 protein, humanIsocitrate Dehydrogenase

Identifiers

PMID33221817
PMCPMC7680457
OpenAlexW3107084545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.