Evidence map›Paper›PMID 33221744›Full record

ArticleAging2020

Hsa_circ_0048179 attenuates free fatty acid-induced steatosis via hsa_circ_0048179/miR-188-3p/GPX4 signaling.

Wenjun Yang, Jinduo Zhao, Ye Zhao, Wenfeng Li, Liang Zhao, Yi Ren, Rongying Ou, Yunsheng Xu

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Role of Circular RNAs in Liver Diseases.International journal of medical sciences · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Circular RNAs in Liver Diseases.Advances in experimental medicine and biology · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. [Regulatory mechanism and potential value of circular RNA in nonalcoholic fatty liver disease progression].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wenjun YangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jinduo ZhaoDepartment of Gynaecology and Obstetrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ye ZhaoDepartment of Gynaecology and Obstetrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Wenfeng LiLaboratory for Advanced Interdisciplinary Research, Institutes of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Liang ZhaoLaboratory for Advanced Interdisciplinary Research, Institutes of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yi RenDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32304, USA.
Rongying OuDepartment of Gynaecology and Obstetrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yunsheng XuLaboratory for Advanced Interdisciplinary Research, Institutes of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
First Affiliated Hospital of Wenzhou Medical University · CNWenzhou Medical University · CNFlorida State University · USSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although circular RNAs (circRNAs) are known to play key roles in non-alcoholic fatty liver disease, much about their targets and mechanisms remains unknown. We therefore investigated the actions and mechanisms of hsa_circ_0048179 in an

Indexed as

ApoptosisGene Expression RegulationHepatocytesHep G2 CellsHumansLiverMembrane Potential, MitochondrialMicroRNAsMitochondria, LiverNon-alcoholic Fatty Liver DiseaseOleic AcidPalmitatesPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesRNA, CircularSignal TransductionMicroRNAsMIRN188 microRNA, humanOleic AcidPalmitatesPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesRNA, CircularGPX4hsa_circ_0048179lipid accumulationmiR-188-3pnon-alcoholic fatty liver disease

Identifiers

PMID33221744
PMCPMC7762518
OpenAlexW3109710641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.