Evidence map›Paper›PMID 33221743›Full record

ArticleAging2020

DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder cancer.

Kai Xu, Binshen Chen, Bingkun Li, Chaoming Li, Yiming Zhang, Ning Jiang, Bin Lang

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kai XuDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Binshen ChenDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Bingkun LiDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Chaoming LiDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Yiming ZhangDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Ning JiangDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China.
Bin LangSchool of Health Sciences, Macao Polytechnic Institute, Macao, People's Republic of China.
Southern Medical University · CNZhujiang Hospital · CNMacao Polytechnic University · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of DNA methyltransferase 3B (DNMT3B) in tumorigenesis and development has been widely recognized; however, the mechanism underlying its action remains unclear. Considering its function in

Indexed as

Cell MovementDNA MethylationEpigenesis, GeneticGene SilencingAgedCell Line, TumorDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BFemaleGene Expression Regulation, NeoplasticHepatocyte Nuclear Factor 4HumansMaleMicroRNAsMiddle AgedNeoplasm InvasivenessDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BHepatocyte Nuclear Factor 4HNF4G protein, humanMicroRNAsMIRN34 microRNA, humanNOTCH1 protein, humanReceptor, Notch1bladder cancerDNA methyltransferase 3BmetastasismethylationmiR-34a promotor

Identifiers

PMID33221743
PMCPMC7762500
OpenAlexW3108554470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.