Evidence map›Paper›PMID 33221730›Full record

ArticleThe British journal of ophthalmology2021

Human leucocyte antigen alleles confer susceptibility and progression to Graves' ophthalmopathy in a Southern Chinese population.

Xiaosheng Huang, Guiqin Liu, Shaoyi Mei, Jiamin Cai, Jing Rao, Minzhong Tang, Tianhui Zhu, Wenchiew Chen, Shiming Peng, Yan Wang and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The British journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Xiaosheng Huang *Shenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.ORCID 0000-0002-6375-0816
Guiqin Liu *Shenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Shaoyi MeiShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Jiamin CaiSchool of Ophthalmology & Optometry, Shenzhen University, Shenzhen, Guangdong, China.
Jing RaoShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Minzhong TangCancer Center, Wuzhou Red Cross Hospital, Wuzhou, Guangxi, China.
Tianhui ZhuShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Wenchiew ChenShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Shiming PengShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Yan WangShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Ye YeSchool of Ophthalmology & Optometry, Shenzhen University, Shenzhen, Guangdong, China.
Tong ZhangShenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China.
Zhihui Deng *Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China zhihui_deng@aliyun.com doctorzhaojun@163.com.ORCID 0000-0002-2046-1467
Jun Zhao *Shenzhen Eye Institute, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen, Guangdong, China zhihui_deng@aliyun.com doctorzhaojun@163.com.ORCID 0000-0002-7285-5812
Jinan University · CNShenzhen University · CNShenzhen Blood Center · CNWuzhou Red Cross Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the contributions of human leucocyte antigen (

methodsEight HLA loci were genotyped and analysed in 272 unrelated patients with Graves' disease (GD) or the proptosis and myogenic phenotypes of GO, and 411 ethnically matched control subjects.

resultsThe allele frequencies of

conclusionsThe

Indexed as

Graves OphthalmopathyAllelesChinaEpitopesGene FrequencyGraves DiseaseHaplotypesHLA-A AntigensHLA-B AntigensHLA-DQ beta-ChainsHLA-DRB1 ChainsHumansPeptidesEpitopesHLA-A AntigensHLA-B AntigensHLA-DQ beta-ChainsHLA-DRB1 ChainsPeptidesGeneticsImmunologyOrbit

Identifiers

PMID33221730
PMCPMC8479741
OpenAlexW3109414999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.