Evidence map›Paper›PMID 33221625›Full record

ReviewJournal of photochemistry and photobiology. B, Biology2020

The bioenergetics of COVID-19 immunopathology and the therapeutic potential of biophysical radiances.

Arzhan Surazakov, Anna Klassen, Oksana Gizinger

Open access · greenAbstract readReview
In one paragraph

Review in Journal of photochemistry and photobiology. B, Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Obesity exacerbates giardiasis: metabolic, intestinal, and immune response in high-fat diet-fed gerbils.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  2. COVID-19's immuno-pathology and cardiovascular diseases.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023
    Review
  3. Article
  4. Nitric Oxide: The Missing Factor in COVID-19 Severity?Medical sciences (Basel, Switzerland) · 2021
    Article
  5. Therapeutic approaches for SARS-CoV-2 infection.Methods (San Diego, Calif.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arzhan SurazakovRadiant Life Technologies, Ltd., 10 Chalkokondyli Street, Amaral 7, Office 101 Lykavitos, P.C.1071 Nicosia, Cyprus. Electronic address: arzhan@radiant-life-technologies.com.
Anna KlassenNo affiliation, Valdayskaya 73, pos. Belmesevo, Barnaul, 656901, Russia.
Oksana GizingerDepartment of Microbiology and Virology, Department of Immunology and Allergology, Medical Institute, RUDN University, Moscow, Russia.
Peoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In developing an effective clinical tool against COVID-19, we need to consider why SARS-CoV-2 infections develop along remarkably different trajectories: from completely asymptomatic to a severe course of disease. In this paper we hypothesize that the progressive exhaustion and loss of lymphocytes associated with severe stages of COVID-19 result from an intracellular energy deficit in an organism which has already been depleted by preexisting chronic diseases, acute psychological stress and the aging process. A bioenergetics view of COVID-19 immunopathology opens a new biophysical opportunity to enhance impaired immune function via proposed pathways of photomagnetic catalysis of ATP synthesis, regenerative photobiomodulation and the ultrasonic acceleration of cell restructuring. Moreover, we suggest that a coherent application of multiple biophysical radiances (coMra) may synergistically enhance energy-matter-information kinetics of basal self-regeneration of cells and thus improve immune function and accelerate recovery.

Indexed as

Biophysical PhenomenaCOVID-19Energy MetabolismHumansLow-Level Light TherapyUltrasonic TherapyBioenergeticscoMraCOVID-19Low level infrared laserMagnetic fieldPhotobiomodulationUltrasound

Identifiers

PMID33221625
PMCPMC7659653
OpenAlexW3100893239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.