Evidence map›Paper›PMID 33221594›Full record

Trial reportEnvironment international2021

Short-term differences in cardiac function following controlled exposure to cookstove air pollution: The subclinical tests on volunteers exposed to smoke (STOVES) study.

Tom Cole-Hunter, Radhika Dhingra, Kristen M Fedak, Nicholas Good, Christian L'Orange, Gary Luckasen, John Mehaffy, Ethan Walker, Ander Wilson, John Balmes and 5 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Health impacts of PMBMC public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Tom Cole-HunterDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA; Centre for Air Pollution, Energy, and Health Research, University of New South Wales, Sydney, NSW, Australia; International Laboratory for Air Quality and Health, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD, Australia; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Radhika DhingraDepartment of Environmental Sciences and Engineering, University of North Carolina, NC, USA; Environmental Public Health Division, United States Environmental Protection Agency, Chapel Hill, NC, USA.
Kristen M FedakDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Nicholas GoodDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Christian L'OrangeDepartment of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.
Gary LuckasenHeart Center of the Rockies, Fort Collins, CO, USA.
John MehaffyDepartment of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.
Ethan WalkerDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Ander WilsonDepartment of Statistics, Colorado State University, Fort Collins, CO, USA.
John BalmesDepartment of Medicine, University of California, San Francisco, CA, USA.
Robert D BrookDivision of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Maggie L ClarkDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Robert B DevlinEnvironmental Public Health Division, United States Environmental Protection Agency, Chapel Hill, NC, USA.
John VolckensDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA; Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.
Jennifer L PeelDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Colorado State University · USEnvironmental Protection Agency · USUniversity of California, San Francisco · USUniversity of Michigan–Ann Arbor · US

Funding

Cookstove air pollution: Emission profiles and subclinical effects of exposureR01ES023688 · NIEHS · COLORADO STATE UNIVERSITY · PI PEEL, JENNIFER L, VOLCKENS, JOHN · 2014 to 2018
$2.9M
NIEHS NIH HHS R01 ES023688
6 · The paper itself

Abstract

backgroundExposure to household air pollution from solid fuel combustion for cooking and heating is an important risk factor for premature death and disability worldwide. Current evidence supports an association of ambient air pollution with cardiovascular disease but is limited for household air pollution and for cardiac function. Controlled exposure studies can complement evidence provided by field studies.

objectivesTo investigate effects of short-term, controlled exposures to emissions from five cookstoves on measures of cardiac function.

methodsForty-eight healthy adults (46% female; 20-36 years) participated in six, 2-h exposures ('treatments'), including emissions from five cookstoves and a filtered-air control. Target fine particulate matter (PM

resultsShort-term differences in SDNN (standard deviation of duration of all NN intervals) and VLF (very-low frequency power) existed for several cookstoves compared to control. While all cookstoves compared to control followed a similar trend for SDNN, the greatest effect was seen immediately following three stone fire (β = -0.13 ms {%}; 95% confidence interval = -0.22, -0.03%), which reversed in direction at 3 h (0.03%; -0.06, 0.13%). VLF results were similar in direction and timing to SDNN; however, other HRV or cardiac repolarization results were not similar to those for SDNN. DISCUSSION: We observed some evidence of short-term, effects on HRV immediately following cookstove treatments compared to control. Our results suggest that cookstoves with lower PM

Indexed as

Air PollutantsAir PollutionAir Pollution, IndoorHousehold ArticlesAdultCookingFemaleHumansMaleParticulate MatterSmokeVolunteersAir PollutantsParticulate MatterSmokeCardiac repolarizationCookstoveFine particulate matterHealthy adultHeart rate variabilityHousehold air pollution

Identifiers

PMID33221594
PMCPMC7775898
OpenAlexW3100812895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.