Evidence map›Paper›PMID 33221591›Full record

ReviewCurrent opinion in neurobiology2020

Whole-brain interactions underlying zebrafish behavior.

Matthew D Loring, Eric E Thomson, Eva A Naumann

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Neurobiology of mitochondrial dynamics in sleep.The Journal of physiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Understanding collective behavior through neurobiology.Current opinion in neurobiology · 2024
    Review
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Review
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew D LoringDuke School of Medicine, Department of Neurobiology, Durham, NC 27710, United States.
Eric E ThomsonDuke School of Medicine, Department of Neurobiology, Durham, NC 27710, United States.
Eva A NaumannDuke School of Medicine, Department of Neurobiology, Durham, NC 27710, United States. Electronic address: eva.naumann@duke.edu.
Duke University · US

Funding

Parallelized Imaging and Automated Analysis of Zebrafish Assays with a Gigapixel MicroscopeR44OD024879 · OD · RAMONA OPTICS, INC. · PI HARFOUCHE, MARK · 2018 to 2022
$3.5M
Real-time, all-optical interrogation of neural microcircuitry in the pretectumR34NS116738 · NINDS · DUKE UNIVERSITY · PI NAUMANN, EVA AIMABLE, PEARSON, JOHN · 2020 to 2020
$714k
NIH HHS R44 OD024879NINDS NIH HHS R34 NS116738
6 · The paper itself

Abstract

Detailed quantification of neural dynamics across the entire brain will be the key to genuinely understanding perception and behavior. With the recent developments in microscopy and biosensor engineering, the zebrafish has made a grand entrance in neuroscience as its small size and optical transparency enable imaging access to its entire brain at cellular and even subcellular resolution. However, until recently many neurobiological insights were largely correlational or provided little mechanistic insight into the brain-wide population dynamics generated by diverse types of neurons. Now with increasingly sophisticated behavioral, imaging, and causal intervention paradigms, zebrafish are revealing how entire vertebrate brains function. Here we review recent research that fulfills promises made by the early wave of technical advances. These studies reveal new features of brain-wide neural processing and the importance of integrative investigation and computational modelling. Moreover, we outline the future tools necessary for solving broader brain-scale circuit problems.

Indexed as

NeurosciencesZebrafishAnimalsBrainNeurons

Identifiers

PMID33221591
PMCPMC10697041
OpenAlexW3100109073

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.