ArticleUrology2021
Characteristics Associated With Depression, Anxiety, and Social Isolation in Adults With Spina Bifida.
Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Transitional urology: a comprehensive review of the transitional care process.Nature reviews. Urology · 2026Review
- Article
- Reproductive Education and Sexual Abuse Among Individuals With Spina Bifida: A Mixed Methods Study.Archives of rehabilitation research and clinical translation · 2025Article
- Changes and Needs Experienced by People Aging With Spina Bifida and Hydrocephalus.The Gerontologist · 2025Article
- Memory in Spina Bifida, from Childhood to Adulthood: A Systematic Review.Journal of clinical medicine · 2024Review
- The impact of the pandemic on physical and functional disabilities in children and adolescents with spina bifida.Spinal cord series and cases · 2024Article
- Psychosocial needs and outcomes of adults with spina bifida: A scoping review, 1974-2023.Health care transitions · 2024Article
- Cognition and emotional distress in middle-aged and older adults with spina bifida myelomeningocele.PloS one · 2024Article
- Article
- Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis.Frontiers in neurology · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo identify demographic and clinical characteristics associated with depression, anxiety, and social isolation among adults with spina bifida. We hypothesize that lower urinary tract dysfunction is associated with poor psychosocial outcomes.
methodsAn anonymous survey was distributed via Facebook advertising to individuals with congenital urologic conditions. Adults with spina bifida were included in our analysis. Lower urinary tract dysfunction was assessed with the Neurogenic Bladder Symptom Score. Depression, anxiety, and social isolation T-scores were measured using Patient-Reported Outcome Measures Information System instruments. A composite depression-anxiety score was calculated. Separate adjusted linear models assessed the association between lower urinary tract dysfunction and depression, anxiety, composite depression-anxiety, and social isolation.
resultsAround 195 participants were included. Rates of depression, anxiety, and social isolation were 48%, 47%, and 43%, respectively. Comorbid depression and anxiety occurred in 39% of subjects. On adjusted regression analysis, lower urinary tract dysfunction was associated with depression (P < 001), anxiety (P <.001), composite depression-anxiety (P <.001), and social isolation (P = .010).
conclusionDepression, anxiety, and social isolation are common in individuals with spina bifida relative to the general population, and associated with lower urinary tract dysfunction. Interventions focused on optimizing lower urinary tract symptoms and function, transition-age adults, group psychotherapy, and comorbid depression and anxiety may be of particular value in this population.
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