Evidence map›Paper›PMID 33220925›Full record

ArticleBiochemical and biophysical research communications2021

T-cell dysregulation in COVID-19.

Bahire Kalfaoglu, José Almeida-Santos, Chanidapa Adele Tye, Yorifumi Satou, Masahiro Ono

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  13. Withaferin A for COVID-19: a Network Pharmacology Approach.Applied biochemistry and biotechnology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Bahire KalfaogluDepartment of Life Sciences, Imperial College London, UK.
José Almeida-SantosDepartment of Life Sciences, Imperial College London, UK; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Chanidapa Adele TyeDepartment of Life Sciences, Imperial College London, UK.
Yorifumi SatouJoint Research Center for Human Retrovirus Infection, Kumamoto University, Japan.
Masahiro OnoDepartment of Life Sciences, Imperial College London, UK; International Research Center for Medical Sciences, Kumamoto University, Japan. Electronic address: m.ono@imperial.ac.uk.
Imperial College London · GBKumamoto University · JP

Funding

Medical Research Council MR/S000208/1
6 · The paper itself

Abstract

T-cells play key roles in immunity to COVID-19 as well as the development of severe disease. T-cell immunity to COVID-19 is mediated through differentiated CD4

Indexed as

CD4-Positive T-LymphocytesCOVID-19CytokinesForkhead Transcription FactorsHumansLymphocyte ActivationSARS-CoV-2T-Lymphocytes, CytotoxicCytokinesForkhead Transcription FactorsFOXP3 protein, human

Identifiers

PMID33220925
PMCPMC7648511
OpenAlexW3105440841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.