SynthesisTravel medicine and infectious disease
Maternal clinical characteristics and perinatal outcomes among pregnant women with coronavirus disease 2019. A systematic review.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The prevalence of mental ill-health in women during pregnancy and after childbirth during the Covid-19 pandemic: a systematic review and Meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Pooled it
- Pooled it
- Pre-existing anti-polyethylene glycol antibodies in pregnant women and newborns.Journal of nanobiotechnology · 2026Observational
- Paradigm shift in utilization of blood and blood components during COVID pandemic among pregnant women in India.Bioinformation · 2026Article
- Listening to the women's experience of perinatal domestic violence during the COVID-19 pandemic: a qualitative content analysis.BMC pregnancy and childbirth · 2025Article
- Three-year impact of COVID-19 pandemic on hospitalized twin pregnancies: evaluation of characteristics and changes in antibiotic prescribing.Frontiers in medicine · 2025Article
- The Legacy of the COVID-19 Pandemic: Impact on Infant and Maternal and Health from an Appalachian Academic Medical Center.Children (Basel, Switzerland) · 2024Article
- COVID-19's Effect in Pregnancy and Vertical Transmission: A Systematic Review.International journal of preventive medicine · 2024Review
- Clinical and epidemiological aspects of severe acute respiratory infection: before and during the first year of the COVID-19 pandemic in Brazil.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023Article
- A propensity score matching study: The prevalence of mental health problems among pregnant women at first antenatal care increased in Chongqing during the first wave of the COVID-19 pandemic.Frontiers in public health · 2023Article
- Observational cohort study of perinatal outcomes of women with COVID-19.Journal of infection and public health · 2022Observational
- The Lived Experiences of Women without COVID-19 in Breastfeeding Their Infants during the Pandemic: A Descriptive Phenomenological Study.International journal of environmental research and public health · 2022Article
- Are in-hospital COVID-19-related mortality and morbidity in pregnancy associated with gestational age?Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Article
- Effects of spike protein and toxin-like peptides found in COVID-19 patients on human 3D neuronal/glial model undergoing differentiation: Possible implications for SARS-CoV-2 impact on brain development.Reproductive toxicology (Elmsford, N.Y.) · 2022Article
- Unravelling the dynamics of the COVID-19 pandemic with the effect of vaccination, vertical transmission and hospitalization.Results in physics · 2022Article
- Clinical characteristics and maternal perinatal outcome in women with a confirmed diagnosis of COVID-19 in a hospital in Peru. Retrospective cohort studyRevista colombiana de obstetricia y ginecologia · 2022Article
- Article
- Research progresses in vertical transmission of SARS-CoV-2 among infants born to mothers with COVID-19.Future virology · 2022Article
- Coronavirus and Pregnancy: The Challenges of the 21Frontiers in microbiology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the maternal clinical characteristics, maternal and perinatal outcomes in COVID-19-positive pregnant women.
methodsArticles in all languages on the SARS-CoV-2 infection in pregnant women were sought from MEDLINE, EMBASE, Cochrane Library and LILACS; China National Knowledge Infrastructure Database (CNKI), Chinese Science and Technology Periodical Database (VIP) and Wan Fang Data between December 1, 2019 and April 27, 2020. Bulletins and national reports were also searched.
resultsFrom 12,168 retrieved articles, 143 were selected for full-text assessment; 33 for descriptive analyses, and 4 case-controls for meta-analysis. In 322 infected pregnant women, aged 20-45 years, the most frequent maternal comorbidity was obesity (24.2%). Forty-two (28.4%) were asymptomatic at admission. Cough (n = 148,59.7%) and fever (n = 147,59.3%) were the most prevalent symptoms. In the meta-analysis, fever (OR: 0.13,95% CI 0.05 to 0.36) and cough (0.26,95% CI 0.11 to 0.59) were lower in pregnant women with COVID-19 than non-pregnant women with COVID-19.195 (60.6%) delivered, and 125 (38.8%) remained pregnant during the study. Cesarean was reported in 99 (50.8%) women and vaginal delivery in 64 (32.8%). The main adverse obstetric outcome was premature birth (n = 37,18.9%). Thirty patients (10.3%) with COVID-19-related complications required intensive care, one (0.3%) died. SARS-CoV-2 was absent in breast milk, amniotic fluid, placenta or umbilical cord blood.
conclusionsThe maternal clinical characteristics of COVID-19-positive pregnant include frequently fever and cough; however significantly less frequently than non-pregnant women with COVID-19. Iatrogenic preterm birth is the main adverse obstetric outcome. Current data does not support vertical transmission in the third trimester.
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