Cold shock induces novel nuclear bodies in Xenopus oocytes.

Ji-Long Liu, Joseph G Gall

Open access · greenAbstract readReview

In one paragraph

Review in Experimental cell research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.1field-weighted citation impact, top 54% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

Functional State of Lampbrush Chromosomes in Early Vitellogenic Oocytes of Hibernating FrogsJournal of developmental biology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Ji-Long LiuDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD, 21218, USA; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China. Electronic address: jilong.liu@dpag.ox.ac.uk.

Joseph G GallDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD, 21218, USA. Electronic address: gall@carnegiescience.edu.

Carnegie Institution for Science · USShanghaiTech University · CN

Funding

THE ORGANIZATION OF ANIMAL CELL NUCLEIR01GM033397 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GALL, JOSEPH G. · 1985 to 2019

$8.4M

THE ORGANIZATION OF ANIMAL CELL NUCLEIR37GM033397 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GALL, JOSEPH G. · 1990 to 1999

–

Medical Research Council MC_U137788471Medical Research Council MC_UU_12021/3NIGMS NIH HHS R01 GM033397NIGMS NIH HHS R37 GM033397

6 · The paper itself

Abstract

Here we describe novel spherical structures that are induced by cold shock on the lampbrush chromosomes (LBCs) of Xenopus laevis oocytes. We call these structures cold bodies or C-bodies. C-bodies are distributed symmetrically on homologous LBCs, with a pattern similar to that of 5S rDNA. Neither active transcription nor translation is necessary for their formation. Similar protrusions occur on the edges of some nucleoli. Endogenous LBCs as well as those derived from injected sperm form C-bodies under cold shock conditions. The function of C-bodies is unknown.

Indexed as

Cold-Shock ResponseAnimalsCell NucleusCell Nucleus StructuresChromosomesFemaleOocytesXenopus laevisChromatinCold bodyNucleolusOocyteSpermXenopus

Identifiers

PMID33220259

DOI10.1016/j.yexcr.2020.112386

PMCPMC7771896

OpenAlexW3098015050

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.