Evidence map›Paper›PMID 33220174›Full record

ArticleDevelopmental cell2020

N

Jie Du, Wang Liao, Weicheng Liu, Dilip K Deb, Lei He, Phillip J Hsu, Tivoli Nguyen, Linda Zhang, Marc Bissonnette, Chuan He and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Developmental cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Manipulation therapy alleviates neuropathic painThe Korean journal of pain · 2026
    Article
  3. Regulation of mCell biology and toxicology · 2026
    Review
  4. tRNA mCellular & molecular immunology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. RNA mCell investigation · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. FTO controls CD8Cell death & disease · 2025
    Article
  18. Regulation and application of mScience China. Life sciences · 2025
    Review
  19. The Role of MClinical reviews in allergy & immunology · 2025
    Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jie DuDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA; Institute of Biomedical Research, Shanxi Medical University, Taiyuan, Shanxi, China.
Wang LiaoDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA; Department of Cardiology, Hainan General Hospital, Hainan Clinical Research Institute, Haikou, Hainan, China.
Weicheng LiuDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.
Dilip K DebDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.
Lei HeDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.
Phillip J HsuDepartments of Chemistry, Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Tivoli NguyenDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.
Linda ZhangDepartments of Chemistry, Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Marc BissonnetteDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.
Chuan HeDepartments of Chemistry, Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.
Yan Chun LiDepartment of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA. Electronic address: cyan@medicine.bsd.uchicago.edu.
University of Chicago · USHainan General Hospital · CNShanxi Medical University · CN

Funding

The Institute for Translational MedicineUL1TR002389 · NCATS · UNIVERSITY OF CHICAGO · PI Joshua J Jacobs, DAVID O MELTZER · 2017 to 2026
$71.6M
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Development of 5hmC and 5mC biomarkers in cell-free circulating DNA for sensitive colon cancer detection and prognosisU01CA217078 · NCI · UNIVERSITY OF CHICAGO · PI BISSONNETTE, BRUCE MARC, ZHANG, WEI · 2017 to 2021
$3.2M
Roles of m6A mRNA Methylation in Innate ImmunityR01AI151162 · NIAID · UNIVERSITY OF CHICAGO · PI LI, YAN CHUN · 2020 to 2024
$2.0M
Macrophage m6A mRNA Methylation in SepsisR21AI140152 · NIAID · UNIVERSITY OF CHICAGO · PI LI, YAN CHUN · 2018 to 2019
$446k
NCATS NIH HHS UL1 TR002389NCI NIH HHS U01 CA217078NHGRI NIH HHS RM1 HG008935NIAID NIH HHS R01 AI151162NIAID NIH HHS R21 AI140152
6 · The paper itself

Abstract

Bacterial infection triggers a cytokine storm that needs to be resolved to maintain the host's wellbeing. Here, we report that ablation of m

Indexed as

Macrophage ActivationRNA Processing, Post-TranscriptionalAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsCells, CulturedFeedback, PhysiologicalFemaleHEK293 CellsHumansMaleMethylationMethyltransferasesMiceMice, Inbred C57BLRAW 264.7 CellsAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, mouseMethyltransferasesMettl14 protein, mouseN-methyladenosineRNA-Binding ProteinsRNA, MessengerSocs1 protein, mouseSuppressor of Cytokine Signaling 1 ProteinTlr4 protein, mouseToll-Like Receptor 4TristetraprolinYthdf1 protein, mouseZfp36 protein, mousebacterial infectioncytokine stormFTOm(6)A methylationmacrophageMETTL14negative feedbacksepsisSOCS1YTHDF1

Identifiers

PMID33220174
PMCPMC7755741
OpenAlexW3103567189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.